Somatic mutations in solid tumors: a spectrum at the service of diagnostic armamentarium or an indecipherable puzzle? The morphological eyes looking for BRAF and somatic molecular detections on cyto-histological samples [PDF]
This review article deals with the analysis and the detection of the morphological features associated with somatic mutations, mostly BRAF(V600E) mutation, on both cytological and histological samples of carcinomas.
Abildgaard +112 more
core +1 more source
A Case Report of Hairy Cell Leukemia Presenting Concomitantly with Sweet Syndrome
Hairy cell leukemia and Sweet syndrome are both uncommon hematological diagnoses. We present a patient who was admitted with fevers, pancytopenia, pneumonia, and rash.
Mohammad Alkayem, Waina Cheng
doaj +1 more source
Recommendations of the SFH (French Society of Haematology) for the diagnosis, treatment and follow-up of hairy cell leukaemia [PDF]
International audienceHairy cell leukaemia (HCL) is a rare haematological malignancy, with approximately 175 new incident cases in France. Diagnosis is based on a careful examination of the blood smear and immunophenotyping of the tumour cells, with a ...
Alain Delmer +10 more
core +2 more sources
Plasma cell leukemia mimicking hairy cell leukemia
A42-year-old female presented with fever and shortness of breath, and was diagnosed with community acquired pneumonia. On presentation she was found to have a white cell count of 13 · 10/L, hemoglobin of 7.1 g/dL and platelets of 51 · 10/L. Peripheral blood smear showed left shift and many cells with hairy projections (56%) (See Fig.
Hanbali, Amr +2 more
openaire +2 more sources
BRAF V600E-Negative Hairy Cell Leukaemia
Since the initial report of the BRAF V600E mutation in hairy cell leukemia, numerous investigators have demonstrated the presence of this activating mutation in nearly all cases of this disease.
Stephen E. Langabeer +4 more
doaj +1 more source
«White spleen» in hairy cell leukemia
«White spleen» in hairy cell ...
V. M. Milosavljević +4 more
doaj +1 more source
Estimating the prevalence of hematological malignancies and precursor conditions using data from Haematological Malignancy Research Network (HMRN) [PDF]
Objective: Well-established cancer registries that routinely link to death registrations can estimate prevalence directly by counting patients alive at a particular point in time (observed prevalence).
Crouch, Simon +4 more
core +1 more source
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente +5 more
wiley +1 more source
Plasma cell leukemia (PCL) is defined by the presence of more than 2 × 109/L PCs in the peripheral blood. It is a very rare type of leukemia with poor outcome. In this case, we report a PCL case with peripheral blood morphology of hairy cell leukemia. We
Nahlah Alghasham +3 more
doaj +1 more source
Differential Diagnoses of Systemic Mastocytosis in Routinely Processed Bone Marrow Biopsy Specimens: A Review [PDF]
Diagnosis of systemic mastocytosis (SM) is mainly based on the morphological demonstration of compact mast cell infiltrates in various tissue sites. In almost all patients such infiltrates are detected in the bone marrow.
Horny, H. -P., Sotlar, K., Valent, P.
core +1 more source

