Results 41 to 50 of about 22,302 (228)

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Hairy Cell Leukemia Variant Masquerading as Acute Leukemia: A Rare Case Report [PDF]

Middle East Journal of Cancer
The key purpose of this report is to present an uncommon case of hairy cell leukemia variant (HCLv). HCLv is found to be a striking clinico-pathological condition which encompasses the features of classical hairy cell leukemia (cHCL) as well as B cell ...
Shruthi Swamy, Shashidhar Karpurmath, Manjunath Nandennavar, Veerendra Angadi   +3 more
doaj   +1 more source

Massive splenomegaly in hairy cell leukemia causing urinary retention

Clinical Case Reports, 2021
Hairy cell leukemia can cause massive splenomegaly which may lead to urinary retention and constipation. Patients usually require a splenectomy for relief of symptoms.
Mohammad Ammad Ud Din, Joel Shapiro, Ronald Sham   +2 more
doaj   +1 more source

Tumor necrosis factor-alpha regulates the expression of inducible costimulator receptor ligand on CD34+ progenitor cells during differentiation into antigen presenting cells [PDF]

, 2001
The inducible costimulator receptor (ICOS) is a third member of the CD28 receptor family that regulates T cell activation and function. ICOS binds to a newly identified ligand on antigen presenting cells different from the CD152 ligands CD80 and CD86. We
Aicher, A, Clark, EA, Daemen, K, Hayden-Ledbetter, M, Irgang, M, Korner, I, Ledbetter, JA, Pezzutto, A, Richter, G, Westermann, J   +9 more
core  

Diagnosis of occult tuberculosis in hematological malignancy by enumeration of antigen-specific T cells. [PDF]

, 2006
n ...
Cerri, Stefania, Ewer, K, Fabbri, Leonardo, Lalvani, A., Losi, Monica, Luppi, Fabrizio, Luppi, Mario, Millington, Ka, Potenza, Leonardo, Richeldi, Luca, Roversi, P, Torelli, Giuseppe   +11 more
core   +1 more source

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

Pancytopenia in a 70-Year-Old African-American Male: An Unusual Presentation of a Rare Disease

Case Reports in Hematology, 2014
Hairy cell leukemia is a rare lymphoid neoplasm arising from mature B-lymphocytes. Clinically, the disease presents with splenomegaly and abdominal discomfort, frequent infections, fatigue and bleeding because of related cytopenias. Bone marrow biopsy is
Aibek E. Mirrakhimov, Alaa M. Ali, Aram Barbaryan, Nwabundo Anusim, Raya Saba, Shawn G. Kwatra, Nasir Hussain, Teresita Zdunek, Alan D. Gilman   +8 more
doaj   +1 more source

Targeted sequencing of BRAF by MinION in archival Formalin-Fixed Paraffin-Embedded specimens allows to discriminate between Hairy Cell Leukemia and Hair Cell Leukemia Variant [PDF]

, 2016
Targeted sequencing of BRAF by MinION in archival Formalin-Fixed Paraffin-Embedded specimens allows to discriminate between Hairy Cell Leukemia and Hair Cell Leukemia ...
ARANCIO, Walter, Cancila, Valeria, FLORENA, Ada Maria, GULINO, Alessandro, LO BOSCO, Giosue', RAMPELLO, Federica, TRIPODO, Claudio   +6 more
core  

Drug-perturbation-based stratification of blood cancer [PDF]

, 2018
As new generations of targeted therapies emerge and tumor genome sequencing discovers increasingly comprehensive mutation repertoires, the functional relationships of mutations to tumor phenotypes remain largely unknown.
Dietrich, Sascha, et al, Rossi, Davide, Zenz, Thorsten   +3 more
core   +1 more source

TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network

Advanced Science, EarlyView.
A retinoic acid receptor agonist, TTNPB, drives the efficient generation of advanced neural stem cells (ANSCs) from human pluripotent stem cells. TTNPB‐centered chromatin remodeling and metabolic reprogramming, promote neuroectoderm commitment. The resulting cells show robust neural potential and functional efficacy in a rat depression model.
Ruilin Du, Yudi Ren, Qiaoqiao Meng, Peng Wei, Ruyu Zhu, Junjie Bao, Ye Yang, Shuo Yan, Chaorong Yue, Xueying Zhu, Shuo Cao, Chunxia Hao, Wei Sun, Yongli Song, Xihe Li, Zhimin Wu, Siqin Bao, Yanglin Chen   +17 more
wiley   +1 more source