Results 91 to 100 of about 6,725,901 (296)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Oscillation and non-oscillation of half-linear differential equations with coeffcients determined by functions having mean values

open access: yes, 2018
The paper belongs to the qualitative theory of half-linear equations which are located between linear and non-linear equations and, at the same time, between ordinary and partial differential equations.
P. Hasil, M. Veselý
semanticscholar   +1 more source

Some New Half-Linear Integral Inequalities on Time Scales and Applications

open access: yesDiscrete Dynamics in Nature and Society, 2019
The main aim of this paper is to establish some new half-linear integral inequalities on time scales. Our results not only extend and complement some known integral inequalities, but also provide a handy tool for the study of qualitative properties of ...
Haidong Liu
semanticscholar   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

On conjugacy of second-order half-linear differential equations on the real axis

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2016
Some conjugacy criteria are given for the equation $$ \big(|u'|^{\alpha}\operatorname{sgn}u'\big)'+p(t)|u|^{\alpha}\operatorname{sgn} u=0, $$ where $p\colon\mathbb{R} \to \mathbb{R}$ is a locally integrable function and $\alpha>0$, which generalise and ...
Jiří Šremr
doaj   +1 more source

Lyapunov-type inequalities for higher-order half-linear difference equations

open access: yesJournal of Inequalities and Applications, 2020
In this paper, we will establish some new Lyapunov-type inequalities for some higher-order superlinear–sublinear difference equations with boundary conditions.
Haidong Liu
doaj   +1 more source

Applications of generalized trigonometric functions with two parameters II

open access: yes, 2019
Generalized trigonometric functions (GTFs) are simple generalization of the classical trigonometric functions. GTFs are deeply related to the $p$-Laplacian, which is known as a typical nonlinear differential operator. Compared to GTFs with one parameter,
Takeuchi, Shingo
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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