Results 131 to 140 of about 6,725,901 (296)
Solutions of Riemann–Weber type half-linear differential equation
, 2017 We establish an asymptotic formula for a pair of linearly independent solutions of the subcritical Riemann–Weber type half-linear differential equation. We also complement the results of the author and M. Ünal, Acta Math. Hungar.
O. Doslý
semanticscholar +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Prediction of Thermal Behavior of Pervious Concrete Pavements in Winter [PDF]
, 2017 Because application of pervious concrete pavement (PCPs) has extended to cold-climate regions of the United States, the safety and mobility of PCP installations during the winter season need to be maintained.
Chen, Zhao +3 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Oscillation constant for modified Euler type half-linear equations
Electronic Journal of Differential Equations, 2015 Applying the modified half-linear Prufer angle, we study oscillation properties of the half-linear differential equation $$ [ r(t) t^{p-1} \Phi(x')]' + \frac{s(t)}{t \log^pt} \Phi(x) = 0, \quad \Phi(x)=|x|^{p-1}\hbox{sgn} x.
Petr Hasil, Michal Vesely
doaj
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
A Survey on Oscillation of Impulsive Ordinary Differential Equations
Advances in Difference Equations, 2010 This paper summarizes a series of results on the oscillation of impulsive ordinary differential equations. We consider linear, half-linear, super-half-linear, and nonlinear equations. Several oscillation criteria are given. The Sturmian comparison theory
Fatma Karakoç +2 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source