Results 71 to 80 of about 31,797 (289)

Enhancing Super‐Resolution Spatial Transcriptomics Data by Transfer Learning

open access: yesAdvanced Science, EarlyView.
SpotZoomer employs a transfer‐learning‐based strategy to enhance the resolution of Visium data by leveraging available high‐resolution priors. The resulting super‐resolved maps enable sharper delineation of cell boundaries and more precise inference of cell–cell communication patterns that would otherwise remain obscured at native resolution.
Xiaoyu Li, Lihua Zhang, Wenwen Min
wiley   +1 more source

Closing the Empirical Loop: Autonomous AI Agents Conduct End‐to‐end Research With Human Participants

open access: yesAdvanced Science, EarlyView.
A multi‐agent AI system autonomously executes the complete scientific workflow, from hypothesis to manuscript, across three psychological studies involving 288 participants. The system designs experiments, collects real world data, develops analysis pipelines, and writes manuscripts with theoretical rigor comparable to experienced researchers.
Gabrielle Wehr   +6 more
wiley   +1 more source

CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction

open access: yesAdvanced Science, EarlyView.
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su   +5 more
wiley   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li   +8 more
wiley   +1 more source

Perception as Controlled Hallucination [PDF]

open access: yes, 2023
“Perception is controlled hallucination,” according to proponents of predictive processing accounts of vision. I say they are right that something like this is a consequence of their view but wrong in how they have pursued the idea.
Tiehen, Justin
core   +1 more source

Low frequency right-sided repetitive transcranial magnetic stimulation for refractory psychotic depression with auditory hallucinations: A case report

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
rTMS is a non-invasive and novel stimulation method that has been used to treat major depression. There is insufficient data for the efficacy of rTMS in depression with psychotic features. There is growing evidence to support the therapeutic benefits of
Onur Durmaz, Mehmet Alpay Ates
doaj  

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

The effect of delusion types on treatment response in schizophrenia spectrum

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objective: There isn’t so many study investigating the effect of delusion types on treatment response and prognosis in schizophrenia spectrum. A sectional study in which religious delusions’ effect was investigated; religious delusions were seen 24% of ...
Güler Acar   +2 more
doaj  

Feature Hallucination for Self-supervised Action Recognition

open access: yes
Understanding human actions in videos requires more than raw pixel analysis; it relies on high-level semantic reasoning and effective integration of multimodal features.
Koniusz, Piotr, Wang, Lei
core   +1 more source

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

open access: yesAdvanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy