Results 91 to 100 of about 104,229 (292)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Influence of Different Levels of Load on the Metabolic Profile of Horses – a Review

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Livestock breeding has been carried out for several millennia based on an external assessment, i.e. exterior. Especially in horses that are bred for muscular work, the relationship between the shape of the body structure on the one hand and the purpose ...
Martin Massányi   +3 more
doaj  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

The association between physical fitness and health in a nationally representative sample of Canadian children and youth aged 6 to 17 years

open access: yesHealth Promotion and Chronic Disease Prevention in Canada, 2019
Introduction: This study explored the relationship between physical fitness and indicators of physical and psychosocial health in a nationally representative sample of Canadian children and youth aged 6–17 years.
Justin J. Lang   +2 more
doaj   +1 more source

A Lunar Halo [PDF]

open access: yesNature, 1882
LAST evening, about 7.15 p.m., a lunar halo of a peculiar character was seen here. It was at some distance from the moon, and instead of being, as usual, concentric with this body, was of an oval, or, more strictly speaking, a horse-shoe shape, the lower part of the halo not being complete.
openaire   +2 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

The Music of Spheres [ God as A Geometer ] [PDF]

open access: yesAnastasis: Research in Medieval Culture and Art, 2014
The rediscovery and enhancement of the standards, canons or constructive techniques of the pictorial space used by the masters of the traditional periods in art history, could be a viable alternative to the identity crisis that defines contemporary art ...
Cristian Ungureanu
doaj  

Home - About - Disclaimer - Privacy