Results 271 to 280 of about 468,265 (345)

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

TR-FRET between engineered nanobodies reveals the existence of endogenous CXCR4 oligomers. [PDF]

Commun Biol
Heuninck J, Bobkov V, Grison CM, Fumagalli A, Lescuyer M, Otun O, Bechara C, Lamarque L, Trinquet E, Bachelerie F, Marin P, Mouillac B, Granier S, van der Woning B, de Haard H, Smit MJ, Heukers R, Durroux T.   +17 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Grazing halos reveal differential ecosystem vulnerabilities in vegetated habitats. [PDF]

Ecology
Minguito-Frutos M, Arthur R, Boada J, Marco-Méndez C, Adams MP, Pagès JF, Buñuel X, Pessarrodona A, Turon X, Ballesteros E, Tamburello L, Farina S, Skouradakis G, Kletou D, Cebrian E, Santamaría J, Verdura J, Alcoverro T.   +17 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Residual stress analysis with various thicknesses of Copper films by XRD [PDF]

International Journal of Advances in Applied Mathematics and Mechanics, 2019
Halo Dalshad Omar
doaj  

Rapid amide ligation between α-halo acylsilanes and amines under aqueous conditions. [PDF]

Nat Commun
Xiong W, Zhu W, Pang J, Liu WH.
europepmc   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

State-selective small molecule degraders that preferentially remove aggregates and oligomers. [PDF]

Nat Commun
Luptak J, Clift D, Mukadam A, Benn J, Rhinesmith T, McLaughlin SH, Dodds AC, Lapetaje JE, Sczaniecka-Clift M, France DJ, McEwan WA, James LC.   +11 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source