Results 81 to 90 of about 459,316 (304)

Massive pericardial effusion: A rare and easily missed finding in myocardial perfusion scintigraphy

open access: yesWorld Journal of Nuclear Medicine, 2018
A 72-year-old gentleman underwent myocardial perfusion scintigraphy (MPS) for sinus tachycardia of unknown cause. Baseline electrocardiography (ECG) showed sinus tachycardia and electrical alternans.
Kwan Wu, Boom Kung, Ting Au Yong
doaj   +1 more source

Determination of Dark Matter Halo Mass from Dynamics of Satellite Galaxies

open access: yes, 2017
We show that the mass of a dark matter halo can be inferred from the dynamical status of its satellite galaxies. Using 9 dark-matter simulations of halos like the Milky Way (MW), we find that the present-day substructures in each halo follow a ...
Jing, Y. P.   +4 more
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Dark Matter Subhalos in the Ursa Minor Dwarf Galaxy

open access: yes, 2012
Through numerical simulations, we study the dissolution timescale of the Ursa Minor cold stellar clump, due to the combination of phase-mixing and gravitational encounters with compact dark substructures in the halo of Ursa Minor.
A. Just   +48 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Community analysis and co-occurrence patterns in airway microbial communities during health and disease

open access: yesERJ Open Research, 2019
Ecological relationships between bacteria are important when considering variation in bacterial communities in humans, with such variation playing an important role in both health and disease.
Gisli G. Einarsson   +5 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Comment on "Geoeffectiveness of halo coronal mass ejections" by N. Gopalswamy, S. Yashiro, and S. Akiyama

open access: yes, 2008
Comment on paper: Gopalswamy, N., S. Yashiro, and S. Akiyama (2007), Geoeffectiveness of halo coronal mass ejections, J. Geophys. Res., 112, A06112, doi:10.1029/2006JA012149 Gopalswamy et al.
D.F. Webb   +9 more
core   +1 more source

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