Late‐Stage Functionalization of Peptides on the Solid Phase
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner +2 more
wiley +1 more source
The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve +4 more
wiley +1 more source
Tuning of electronic, optical and lipophilic behaviours of adamantane through various substitutions
Successive tuning of electronic, optical and lipophilic characteristics of adamantane molecules are obtained by various halogen substitutions at bridgehead and bridge positions of adamantane.
Aravindhan R +2 more
doaj +1 more source
Hydrosilane Chemistry: From Historic First Steps to Modern Applications
This review covers the history of hydrosilanes, from their initial discovery to their modern applications. It highlights the pioneering work of chemists like Alfred Stock and Franz Fehér and discusses the modern ways of synthesis and use of hydrosilanes in printed electronics.
Uwe Böhme, Maik Gerwig
wiley +1 more source
Synthesis of Benzopyran Atropisomers via Electrophilic Halogenation
We report a halogenation‐based method for the synthesis of axially chiral benzopyrans, tolerating diverse substituents and halogens (Br, Cl, and I). A double bromination gives bisbenzopyrans with two stereogenic axes. Preliminary enantioselective conditions yield benzopyran atropisomer with up to 56% ee.
Alix Bourhis +3 more
wiley +1 more source
Study on the Synthesis of Fatty Alcohol-polyoxyethylene Ether Chloride Catalyzed by Ionic Liquid
:The cationic surfactant of fatty alcohol-polyoxyethylene ether is a multi-functional surfactant, which played an important role in the industry of detergent, textile and so on.
zhenfangchen +3 more
doaj
Regioselective synthesis of 3-halo-2<i>H</i>-chromenes via decarboxylative halogenation of oxygenated 3-carboxy-2<i>H</i>-chromenes: Application to isoflavonoid synthesis. [PDF]
Kang B +3 more
europepmc +1 more source
Indirect Laser-Mediated Halogenation of Graphene: Implications for Hydrogen Evolution Reaction. [PDF]
Khurshid F +3 more
europepmc +1 more source
How Fe(II)/2-Oxoglutarate Oxygenase Chooses Chlorination over Hydroxylation: Electric Field-Driven Ligand Exchange Governs C-Cl Formation. [PDF]
Jaber Sathik Rifayee SB +6 more
europepmc +1 more source
One-Pot Amidation/C─H Halogenation by an Efficient Electrochemical Cascade. [PDF]
Ponra S +8 more
europepmc +1 more source

