Results 291 to 300 of about 148,467 (378)

Geminal homologative fluorination of carbonyl derivatives <i>en route</i> to 1-fluoro-2-haloethyl skeletons.

Chem Commun (Camb)
Miele M, Castiglione D, Prado-Roller A, Castoldi L, Pace V.   +4 more
europepmc   +1 more source

On-Surface Ullmann-Type Coupling Reactions of Aryl Halide Precursors with Multiple Substituted Sites. [PDF]

Nanomaterials (Basel)
Liu Q, Gao Y, Zhang C.
europepmc   +1 more source

Stable BF2 Boracycles as Versatile Reagents for Selective Ortho C–H Functionalization

Angewandte Chemie, EarlyView.
We report a robust, metal‐free and scalable synthesis of stable BF2 boracycles via directed ortho CH borylation, delivering isolable, shelf‐stable reagents without chromatographic purification. These BF2 boracycles exhibit unique and tunable reactivity, enabling highly selective ipso‐functionalization across a broad range of transformations.
Ganesh H. Shinde, Jonatan Babiker, Michelle Mebrahtu, Anaïs Prigent, Gauthier Foucras, Yogesh N. Aher, Francoise M. Amombo Noa, Magnus J. Johansson, Janez Košmrlj, Ross D. Jansen‐van Vuuren, Thomas Cailly, Henrik Sundén   +11 more
wiley   +1 more source

Stabilization of a protein by a single halogen-based aromatic amplifier. [PDF]

Protein Sci
El Hage K, Dhayalan B, Chen YS, Phillips NB, Whittaker J, Carr K, Whittaker L, Phillips MH, Ismail-Beigi F, Meuwly M, Weiss MA.   +10 more
europepmc   +1 more source

Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions

Angewandte Chemie, EarlyView.
This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan, Parrish Evers, Elexa Scott, John Paul Pezacki   +3 more
wiley   +1 more source

Site-of-Metabolism Prediction with Aleatoric and Epistemic Uncertainty Quantification. [PDF]

J Chem Inf Model
Jacob RA, Wieder O, Chen Y, Mazzolari A, Bergner A, Schleifer KJ, Kirchmair J.   +6 more
europepmc   +1 more source

(Poly)Borylated Species as Modern Reactive Groups toward Unusual Synthetic Applications

Angewandte Chemie, EarlyView.
In this review, we spotlight recent breakthroughs in α‐polyboron‐substituted carbon‐centered intermediates (carbanion, carbocation, radical, and carbene) and polyborylated alkenes. By bridging fundamental reactivity with the application potential of these extraordinary species, we hope this review will serve as a roadmap for harnessing these unique ...
Nadim Eghbarieh, Nicole Hanania, Pinaki Nad, Tipu Alam, Tamir Kish, Ahmad Masarwa   +5 more
wiley   +1 more source

The Active Soil Layer of Thawing Permafrost Is an Emergent Source for Organic Substances of Concern to Water Resources. [PDF]

Environ Sci Technol Lett
Han M, Jin B, Arp HPH.
europepmc   +1 more source

Halide Bond Assisted Double Desymmetrization of Meso‐Dicarboxylic Acids with Symmetrical Olefins via Asymmetric Halogenation

Angewandte Chemie, EarlyView.
This work demonstrates a double desymmetrization of meso‐dicarboxylic acids with symmetrical olefins, constructing complex chiral lactones with six stereocenters in one step. Unexpectedly, the halide bond was found to be crucial in achieving high stereoselectivity.
Qingyu Zhang, Haihui Wang, Ying‐Lung Steve Tse, Ying‐Yeung Yeung   +3 more
wiley   +1 more source