Co‐Expression of Tardive Dyskinesia and Drug‐Induced Parkinsonism in Rats Chronically Treated With Haloperidol [PDF]
Aim We aimed to create a rat model of drug‐induced parkinsonism and tardive dyskinesia by chronic administration of haloperidol and examine the expression of direct and indirect pathway markers in the striatum of the model rats.
Iku Kinoshita +7 more
doaj +4 more sources
Haloperidol decanoate-induced acneiform eruption: A case report
Haloperidol decanoate is a depot preparation of haloperidol, which may rarely cause dermatological side effects among other commonly seen side effects.
Ihsan Aksoy, Mehmet Hamdi Orum
doaj +2 more sources
Srihari Gopal1, Joris Berwaerts1, Isaac Nuamah1, Kasem Akhras2, Danielle Coppola1, Ella Daly1, David Hough1, Joseph Palumbo11Johnson & Johnson Pharmaceutical Research & Development, LLC, Raritan, NJ, USA; 2Johnson & Johnson ...
Srihari Gopal +3 more
doaj +1 more source
Cost-Effectiveness of Long-Acting Injectable Paliperidone Palmitate Versus Haloperidol Decanoate in Maintenance Treatment of Schizophrenia. [PDF]
This study assessed the relative cost-effectiveness of a first generation and a second generation long-acting injectable antipsychotic: haloperidol decanoate (HD) and paliperidone palmitate (PP ...
Rosenheck RA +9 more
europepmc +2 more sources
Clozapine-Induced Gastrointestinal Hypoperfusion Leading to Bowel Ischemia and Secondary Atrial Fibrillation: A Case Report. [PDF]
Introduction Clozapine is a highly effective antipsychotic for treatment‐resistant schizophrenia but carries a risk of rare and serious adverse events. This case highlights a potentially fatal episode of clozapine‐induced gastrointestinal hypoperfusion leading to bowel ischemia and secondary atrial fibrillation in a patient with chronic schizophrenia ...
Kumar S, Chatterjee M.
europepmc +2 more sources
Use of Electroconvulsive Therapy for Treatment-Resistant Schizophrenia in a Patient Unable to Tolerate Clozapine Due to Clozapine-Associated Hyponatremia: A Case Report. [PDF]
Clozapine is regarded as the most effective treatment for patients with treatment‐resistant schizophrenia (TRS). However, serious adverse effects such as hyponatremia may necessitate discontinuation, leaving limited therapeutic alternatives. This case report describes a middle‐aged male with chronic schizophrenia who developed clinically significant ...
Hartley A +3 more
europepmc +2 more sources
Morphological Changes in Direct Pathway Striatal Neurons in a Rat Model of Tardive Dyskinesia. [PDF]
Abstract Background Tardive dyskinesia (TD) and drug‐induced parkinsonism (DIP) arise from prolonged dopamine antagonist use. Although D2 receptor hypersensitivity in the indirect pathway is a proposed mechanism, the role of the direct pathway remains unclear.
Hikichi H +6 more
europepmc +2 more sources
Nuances of Gender Identity for a Transgender Patient Receiving Inpatient Treatment for Paranoid Schizophrenia: A Case Study. [PDF]
Introduction Nearly one‐fourth of individuals diagnosed with schizophrenia may experience symptoms of gender dysphoria. Patients may identify with a gender other than the gender assigned at birth before or after psychotic disorder onset. In either case, the presence of both psychosis and gender dysphoria may complicate evaluation and treatment. Case We
Suri RK +3 more
europepmc +2 more sources
Haloperidol decanoate long-acting injection (HDLAI): Results of a 1-year mirror-image study. [PDF]
Background: We sought to determine clinical outcomes of the prescribing of haloperidol decanoate long-acting injection (HDLAI) at 1 year. Method: A 1-year mirror-image study of 84 inpatients initiated on HDLAI.
Mace S, Dzahini O, O'Hagan M, Taylor D.
europepmc +2 more sources
Leukopenia in a patient on haloperidol decanoate: a case report [PDF]
We are reporting a case of leukopenia developed in a patient on haloperidol decanoate injections. A literature review revealed it as an uncommon side effect of antipsychotics; however, regular monitoring of blood cell count is crucial in patients on ...
Ahmed, Samreen, Warraich, Saima
core +1 more source

