The crystal structure of Haloferax volcanii proliferating cell nuclear antigen reveals unique surface charge characteristics due to halophilic adaptation [PDF]
Background: The high intracellular salt concentration re quired to maintain a halophilic lifestyle poses challenges to haloarchaeal proteins that must stay soluble, stable and functional in this extreme environment.
Bunting, KA +3 more
core +2 more sources
SICLE: A high-throughput tool for extracting evolutionary relationships from phylogenetic trees
We present the phylogeny analysis software SICLE (Sister Clade Extractor), an easy-to-use, high- throughput tool to describe the nearest neighbors to a node of interest in a phylogenetic tree as well as the support value for the relationship.
DeBlasio, Dan, Wiscaver, Jennifer
core +2 more sources
Structure analysis of biologically important prokaryotic glycopolymers [PDF]
Of the many post-translational modifications organisms can undertake, glycosylation is the most prevalent and the most diverse. The research in this thesis focuses on the structural characterisation of glycosylation in two classes of glycopolymer (
Ventura, Valeria Victoria +1 more
core +1 more source
Halophilic and halotolerant microorganisms represent promising sources of salt-tolerant enzymes that could be used in various biotechnological processes where high salt concentrations would otherwise inhibit enzymatic transformations.
Robert Ruginescu +7 more
doaj +1 more source
The Function of Gas Vesicles in Halophilic Archaea and Bacteria: Theories and Experimental Evidence
A few extremely halophilic Archaea (Halobacterium salinarum, Haloquadratum walsbyi, Haloferax mediterranei, Halorubrum vacuolatum, Halogeometricum borinquense, Haloplanus spp.) possess gas vesicles that bestow buoyancy on the cells. Gas vesicles are also
Aharon Oren
doaj +1 more source
Diurnally entrained anticipatory behavior in archaea. [PDF]
By sensing changes in one or few environmental factors biological systems can anticipate future changes in multiple factors over a wide range of time scales (daily to seasonal).
Kenia Whitehead +4 more
doaj +1 more source
Quantitative RNA-seq Analysis Unveils Osmotic and Thermal Adaptation Mechanisms Relevant for Ectoine Production in Chromohalobacter salexigens [PDF]
Quantitative RNA sequencing (RNA-seq) and the complementary phenotypic assays were implemented to investigate the transcriptional responses of Chromohalobacter salexigens to osmotic and heat stress.
Carmen Vargas +6 more
core +2 more sources
Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes
Archaeal lipid‐based liposomes, particularly those containing caldarchaeol (GDGT), were found to significantly prolong the circulation time of vancomycin in rats, matching the pharmacokinetic properties of PEGylated systems. These findings suggest archaeal lipids as promising non‐PEG excipients for parenteral applications to minimize drug clearance ...
Viktor Sedlmayr +9 more
wiley +1 more source
Halophilic microorganisms abound in numerous hypersaline environments, such as salt lakes, salt mines, solar salterns, and salted seafood. In the northwest of Dingbian county (Shaanxi province, China), there exists a belt of hypersaline habitats ...
Yue Ding +10 more
doaj +1 more source
The archaeal protein SepF is essential for cell division in Haloferax volcanii
In most bacteria, cell division depends on tubulin homolog FtsZ and other proteins, such as SepF. Cell division in many archaea also depends on FtsZ. Here, Nußbaum et al.
Phillip Nußbaum +4 more
doaj +1 more source

