Results 91 to 100 of about 1,936 (237)

Optogenetic approaches in neurobiology [PDF]

open access: yes, 2016
peer ...
Babaev,   +4 more
core   +1 more source

Selective activation of striatal indirect pathway suppresses levodopa induced-dyskinesias [PDF]

open access: yes
Levodopa (L-DOPA) administration remains the gold standard therapy for Parkinson's disease (PD). Despite several pharmacological advances in the use of L-DOPA, a high proportion of chronically treated patients continues to suffer disabling involuntary ...
Casado-Polanco, R.   +10 more
core   +1 more source

Controlling the pathological activity of parkinsonian basal nuclei with the basal ganglia network model under light stimulation in the three-state, four-state channelrhodopsin, and three-state halorhodopsin optogenetic models

open access: yesMedical Journal of Tabriz University of Medical Sciences
Background. Parkinson’s disease (PD) is a neurological disorder caused by the dysfunction of the basal nuclei, especially the substantia nigra, and a decrease in dopamine levels in the neural circuits of this part.
Nazlar Ghasemzadeh   +4 more
semanticscholar   +1 more source

Investigation of evolution-related aspects of bacterial rhodopsins [PDF]

open access: yes
We have investigated evolution-related aspects of bacterial rhodopsins, the unique retinal-based energy transducing systems of halophilic archae. The approach was to describe both structural and functional aspects: the structure by sequencing genes to ...

core   +1 more source

Akute optogenetische Stimulation von serotonergen Neuronen in Raphe-Kernen reduziert Zellproliferation im Gyrus dentatus der Maus [PDF]

open access: yes
The subgranular zone of the hippocampal dentate gyrus (DG) is known to be replenished with new-born neurons even after fetal and early postnatal development has completed, a phenomenon called adult neurogenesis.
Araragi, Naozumi
core   +1 more source

Optogenetics in oral and craniofacial research

open access: yesJournal of Zhejiang University SCIENCE B
Optogenetics combines optics and genetic engineering to control specific gene expression and biological functions and has the advantages of precise spatiotemporal control, noninvasiveness, and high efficiency.
Qinmeng Zhang   +5 more
semanticscholar   +1 more source

Microbial Rhodopsins in Optogenetics [PDF]

open access: yes
Microbial rhodopsins are a family of photochemically reactive proteins found in prokaryotes and lower eukaryotes in a variety of habitats. Like the rhodopsins in animal vision, microbial rhodopsins have seven transmembrane helices that form a pocket ...
Kersten, Elise
core   +1 more source

Development of next-generation optical neural silencers [PDF]

open access: yes, 2011
Thesis (S.M.)--Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, 2011.Cataloged from PDF version of thesis.Includes bibliographical references (p.
Chuong, Amy (Amy S.)
core  

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