Results 71 to 80 of about 1,936 (237)
Implantable Light‐Powered Human Designer Cells for Electrical Energy Generation
Advanced Materials, Volume 37, Issue 45, November 13, 2025.Inspired by the eel's electric organ, a miniature implantable biohybrid device is developed to generate electricity under light activation. The device utilizes a light‐dependent ion gradient formation that induced by genetically engineered human designer cells that express light‐sensitive membrane ion channels and proton pumps, working in synergy with ...
Shuai Xue +5 more
wiley +1 more source
Review of Multifunctional Neural Probe
Advanced Materials Interfaces, Volume 12, Issue 21, November 10, 2025.Modern multifunctional neural probes for brain‐machine interfaces extend beyond basic electrical functions to incorporate chemical and optical modalities. This review explores recent advances in multifunctional probes developed for neural signal acquisition and stimulation, highlighting how these innovations enhance the precision of brain activity ...
Ziqi Jia, Yong Kyu Yoon
wiley +1 more source
Advanced Science, Volume 12, Issue 42, November 13, 2025.An AI‐powered system decodes emotional valence from mouse facial expressions, identifying ear dynamics as key indicators. By integrating facial kinematics with synchronized neural recordings, this approach establishes a direct link between behavior and brain activity, advancing automated emotion recognition in animal models.
Yujia Chen +9 more
wiley +1 more source
A Comparative Study of Modern Homology Modeling Algorithms for Rhodopsin Structure Prediction [PDF]
, 2018 Rhodopsins are seven α-helical membrane proteins that are of great importance in chemistry, biology, and modern biotechnology. Any in silico study on rhodopsin properties and functioning requires a high-quality three-dimensional structure.
Chakchir, Oleg B. +7 more
core +1 more source
Electrostatic Influence on Photoisomerization in Bacteriorhodopsin and Halorhodopsin
The Journal of Physical Chemistry B, 2019 Bacteriorhodopsin (bR) and halorhodopsin (hR) are both membrane proteins that transport ions across the cell membrane in halobacteria. Their ion transport function is triggered by photoactivated isomerization of the retinal protonated Schiff base (RPSB) chromophore.
C. Punwong +2 more
openaire +3 more sources
Spatiotemporal control in biomedicine: photoswitchable peptides and foldamers
British Journal of Pharmacology, Volume 182, Issue 19, Page 4458-4465, October 2025.Photopharmacology integrates light‐based technology with pharmacology to achieve precise control over biological processes, offering non‐invasive activation and spatiotemporal regulation of biomolecular activity. Within this field, photoswitchable peptides and foldamers provide a powerful approach in precision medicine, enabling reversible ...
Eszter Erdei +5 more
wiley +1 more source
Health Science Reports, Volume 8, Issue 9, September 2025.ABSTRACT Background and Aims Parkinson's disease (PD) is a progressive neurological condition that consists of both motor and non‐motor symptoms that considerably deteriorate the quality of life. Pharmacological treatments, primarily levodopa, have been used to manage PD. However, side effects such as dyskinesias and motor fluctuations frequently limit
Muhammad Shaheer Bin Faheem +6 more
wiley +1 more source
Nano-Scintillators as Next Generation Tools for Optogenetics [PDF]
, 2020 Optogenetics is a technique that is used to study neural pathways and has the ability to activate or silence synaptic behavior using visible light. Currently, the visible light sources used for optogenetics are surgically implanted into the brain tissue,
Dickey, Ashley
core +1 more source
Characterizing optogenetically mediated rebound effects in anaesthetized mouse primary visual cortex
The Journal of Physiology, Volume 603, Issue 16, Page 4609-4636, 15 August 2025.Abstract figure legend Many studies of cortical circuits use optogenetic activation of inhibitory interneurons to suppress pyramidal cell activity, but after the light is turned off pyramidal cells sometimes show excess spiking, which is called a post‐inhibitory rebound.
Jared T. Shapiro +2 more
wiley +1 more source
Revisiting the Role of Infralimbic Cortex in Fear Extinction with Optogenetics
Journal of Neuroscience, 2015 Previous rodent studies have implicated the infralimbic (IL) subregion of the medial prefrontal cortex in extinction of auditory fear conditioning. However, these studies used pharmacological inactivation or electrical stimulation techniques, which lack ...
F. H. Do-Monte +4 more
semanticscholar +1 more source