Results 41 to 50 of about 95,708 (262)
Jurnal Ilmiah Kebijakan Hukum, 2022 Humanitarian intervention is an act of intervention using armed forces for humanitarian purposes. Indonesia as a country that has a role to participate in maintaining world security and order has the potential to carry out humanitarian interventions. The
Yuditia Nurimaniar +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
LINFOMA DE CÉLULAS T/NK EXTRANODAL SUBTIPO NASAL PRIMÁRIO DE TESTÍCULO: UM RELATO DE CASO
Hematology, Transfusion and Cell TherapyIntrodução: Os Linfomas de Células T/NK extranodal são um subtipo raro e agressivo de linfoma associado com o vírus Epstein-Barr, correspondendo a menos de 2% dos casos de Linfomas T. Sua prevalência é maior na Ásia e América Latina.
SR Simões +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
The Hamming Ball Sampler [PDF]
Journal of the American Statistical Association, 2017 We introduce the Hamming ball sampler, a novel Markov chain Monte Carlo algorithm, for efficient inference in statistical models involving high-dimensional discrete state spaces. The sampling scheme uses an auxiliary variable construction that adaptively truncates the model space allowing iterative exploration of the full model space.
Titsias, M, Yau, C
openaire +5 more sources
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Implementasi Mekanisme Pemberian Hukuman Disiplin di Kementerian Hukum dan HAM
Jurnal Ilmiah Kebijakan Hukum, 2019 Inspektorat Jenderal Kementerian Hukum dan Hak Asasi Manusia masih menghadapi kendala diantaranya adalah perbedaan data hukuman disiplin yang dimiliki.
Oki Wahju Budijanto, Nicken Sarwo Rini
doaj +1 more source
Jurnal HAM, 2021 Fenomena deret tunggu eksekusi mati bukan hanya menjadi masa tunggu terpidana mati dalam proses pengajuan upaya hukum permohonan grasi ke Presiden, tetapi juga menjadi bentuk penghukuman tersendiri bagi para terpidana mati.
Firdaus Firdaus +2 more
doaj +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source