A simple, modular, and unified strategy for the synthesis of reverse‐prenylated hexahydropyrrolo indole alkaloids has been developed. An unusual retrosynthetic disconnection allows for the late introduction of a side chain, which distinguishes many members of this class of natural products.
Daniel Schmelzer +2 more
wiley +1 more source
Hippocampal network activity changes during early epileptogenesis predict subsequent epilepsy
Abstract Objective Despite decades of research, the circuit mechanisms that underlie focal epileptogenesis remain incompletely understood. In this study, we aimed to characterize the changes in hippocampal network activity induced by an epileptogenic insult.
Michael Strüber +13 more
wiley +1 more source
Referral pathways as mechanisms of child maltreatment identification: evidence from a German Childhood-House. [PDF]
Pawils S +3 more
europepmc +1 more source
Natural actomyosin from B. bengalensis exhibited maximum solubility (∼69.9%) at 40°C and stability near neutral pH, with minimum solubility at pH 4. Surface hydrophobicity and emulsifying activity peaked at 50°C, whereas Ca2+‐ATPase and foaming peaked at 40°C. DSC and SDS–PAGE confirmed denaturation above 40°C.
Krishan Kumar Yadav +7 more
wiley +1 more source
[Correction: Does the Innovation Fund Improve Healthcare Provision? A Critical Assessment of the Status of Implementing Successful Innovation Fund Projects into Healthcare Practice]. [PDF]
Lindemann C +16 more
europepmc +1 more source
High‐Order Projection‐Based Upwind Method for Simulation of Transitional Turbulent Flows
In this study, we evaluated the implicit large‐eddy simulation capabilities of the mass‐conserving mixed stress method for transitional turbulent flows and proposed an efficient solution method for large‐scale applications. The results presented in this work show promising outcomes for incompressible aerodynamic flow problems, which can be further ...
Philip L. Lederer +2 more
wiley +1 more source
Iatrogenic ventricular septal defect following papillary muscle premature ventricular contraction ablation: a case report. [PDF]
Benesch Vidal ML +4 more
europepmc +1 more source
What Can Providers' Motivations Tell Us About Healthcare Quality?
ABSTRACT Agency theory suggests that variation in providers' quality of care may be explained by their heterogeneous motivations. We provide novel empirical evidence on the links between different sources of provider motivation and quality of care by combining a unique 4‐year survey dataset on Danish general practitioners' motivations with quality ...
Lucy Margaret Poole +2 more
wiley +1 more source
Socioeconomic disparities in survival among follicular lymphoma patients. [PDF]
von Kroge S +7 more
europepmc +1 more source
One size fails all? EU insolvency law between harmonisation and 28th regime
Abstract The European Union's efforts to harmonise national insolvency laws have long been seen as a key step towards the completion of the Internal Market and, in particular, its Capital Markets Union project. Yet despite years of legislative activity, meaningful convergence has remained elusive.
Wolf‐Georg Ringe
wiley +1 more source

