Results 211 to 220 of about 2,225,625 (302)

Beyond Simple Mimicry: Next‐Generation Geometric Architectures and Future Paradigms in Small‐Molecule and Macrocyclic Peptidomimetics

Angewandte Chemie, EarlyView.
Peptide‐to‐Small Molecule Paradigm: Peptidomimetics have evolved from simple mimicry toward drug‐like scaffolds supported by increasing clinical successes. This Perspective highlights the geometric design principles—linear repetition, convergent fusion, and cyclization—defining the next‐generation peptidomimetic architectures capable of targeting ...
Jesang Lee, Sumin Son, Jeong Yeon Yoo, Ji Hyae Lee, Meehyun Chun, Seung Bum Park   +5 more
wiley   +2 more sources

Persona-Driven Vignettes: A Novel Needs Assessment and Audit Tool for Faculty Development. [PDF]

Cureus
Tong XC, Lee M, Pratt M, Kristof L, Monteiro S, Park S, Chen R, Chan TM.   +7 more
europepmc   +1 more source

Neuroprotection after transient middle cerebral artery occlusion in male rats using kojic acid nanostructured lipid carriers: A behavioral, biochemical, and histological study on hippocampal CA1 region

Animal Models and Experimental Medicine, EarlyView.
This study demonstrates that kojic acid–loaded nanostructured lipid carriers (KA‐NLC) provide significant neuroprotection in a male rat model of middle cerebral artery occlusion (MCAO)–induced stroke. Treatment with KA‐NLCs reduced cerebral edema, improved motor and coordination balance and neurological scores, and enhanced spatial and avoidance memory.
Mobina Gheibi, Erfan Ghadirzadeh, Javid Tebyani, Seyedeh Mohadeseh Moyaedi, Khadijeh Khezri, Majid Saeedi, Ali Siahposht‐Khachaki, Narges Karimi, Melika Pourhossein, Shiva Shadi, Sasan Shafiei, Atena Sharifi‐Razavi   +11 more
wiley   +1 more source

Reproductive Cycle of the Endangered Pabda, Ompok pabda (Hamilton-Bouchanan, 1822) in Bangladesh

Asian Fisheries Science, 2010
B.K. CHAKRABORTY
doaj   +1 more source

Faster-and-tighter nitrogen cycle supports mature forest productivity under elevated CO₂. [PDF]

Sci Adv
Rumeau M, Mayoral C, Sgouridis F, Reay MK, Carrillo Y, Norby RJ, Hamilton L, Hartley IP, Micucci G, Sayer E, Mackenzie AR, Ullah S.   +11 more
europepmc   +1 more source

Defect‐Rich CoNi Prussian Blue Analogues Enable Highly Selective Electrochemical Hydrogen Peroxide Production

Angewandte Chemie, EarlyView.
Introducing [Co(CN)6]3− defects into CoNi Prussian Blue analogues exposes square‐planar Ni–N4 active sites, leading to remarkable H2O2 selectivity during the electrochemical oxygen reduction reaction in alkaline media. ABSTRACT Decentralized electrosynthesis of hydrogen peroxide (H2O2) via the two‐electron oxygen reduction reaction (2e− ORR) offers a ...
Kai Sun, Yu Mao, Yongfang Zhou, Ziyun Wang, Geoffrey I. N. Waterhouse   +4 more
wiley   +2 more sources

Challenging prior assumptions: coexistence of polycystic ovarian morphology and endometriosis on transvaginal ultrasound. [PDF]

Ultrasound Obstet Gynecol
Romeo P, Freger SM, Kalani N, Shishkina A, Aharoni S, Shetty R, Leonardi M.   +6 more
europepmc   +1 more source

Tailoring High‐Valent Iron‐Oxo Species Redox via Extended π‐Fe3d–O2p Orbital Overlapping Toward Chemical‐Efficient Water Purification

Angewandte Chemie, EarlyView.
We address the long‐standing challenge of reactivity–selectivity trade‐off by precisely tuning the redox properties of Fe(IV), rather than simply accelerating its formation, to enable chemically efficient and low‐emission water treatment. ABSTRACT High‐valent iron oxo species (Fe(IV)) are attractive for wastewater treatment because of their high ...
Hongyu Zhou, Junwen Chen, Jiuyi Wang, Xinhao Wang, Qiming Zhang, Shiying Ren, Xuning Li, Li Gao, Shaobin Wang, Xiaoguang Duan   +9 more
wiley   +2 more sources

Risk factors and causes of early death in germ cell tumors: a Global Society for Rare GU tumors study. [PDF]

Br J Cancer
Mego M, Israelyan E, Hamilton RJ, Heidenreich A, Basso U, Giannatempo P, Buchler T, Dieckmann KP, Huddart R, Vincenzi B, Park K, Aparicio J, Tryakin A, Amiri A, Malcharkova P, Claps M, Miletic M, Chaloupkova L, Angerer M, Spiess PE, De Giorgi U, Global Society for Rare GU Tumors.   +21 more
europepmc   +1 more source

Dual d–p hybridization in Ternary PtGaGe Enables Concurrent Activity and Stability Enhancement for Alkaline Oxygen Reduction

Angewandte Chemie, EarlyView.
A unique dual d–p orbital hybridization strategy was established in a ternary PtGaGe alloy catalyst to overcome the longstanding activity–stability trade‐off in oxygen reduction reaction (ORR). Synergistic hybridization between Ga/Ge p orbitals and Pt d orbitals modulates the Pt electronic structure, optimizes oxygen intermediates adsorption, and ...
Qian Zhang, Jinting Wu, Yong‐Chao Zhang, Lijun Tang, Xingchun Shi, Jian Gao, Tiansheng Mu, Xiaoli Zhang, Xiao‐Dong Zhu   +8 more
wiley   +2 more sources