Results 251 to 260 of about 3,567,425 (361)

Magnifying Glass on Sinonasal NUT Carcinoma Heterogeneity via Spatial Transcriptomics

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Nuclear protein in testis (NUT) carcinomas (NCs) are rare, clinically aggressive tumors with characteristic translocation involving NUTM1 and BRD4 genes. While NCs are generally characterized by undifferentiated basaloid cells with focal/abrupt squamous differentiation, tumoral heterogeneity remains unexplored.
Diana Bell   +8 more
wiley   +1 more source

Camizestrant in Combination with Three Globally Approved CDK4/6 Inhibitors in Women with ER+, HER2- Advanced Breast Cancer: Results from SERENA-1. [PDF]

open access: yesClin Cancer Res
Baird RD   +22 more
europepmc   +1 more source

Patient Roles and Patient Knowledge in Learning Health Systems

open access: yesThe International Journal of Health Planning and Management, EarlyView.
ABSTRACT Learning health systems collect and analyse data on an ongoing basis to make real‐time, evidence‐informed decisions. Patient involvement is central to learning health systems. In this perspective paper, we describe implications that LHSs' distinguishing features have for patient involvement.
Cara Evans   +2 more
wiley   +1 more source

Sleep disturbances linked to plasma orexin A levels in patients with bipolar disorder: A preliminary study. [PDF]

open access: yesCompr Psychoneuroendocrinol
Moya-Lacasa C   +7 more
europepmc   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner   +7 more
wiley   +1 more source

Expectations and Speculation in the US Natural Gas Market

open access: yesInternational Journal of Finance &Economics, EarlyView.
ABSTRACT This paper aims to assess the role of expectations as a determinant of the real price of natural gas in the US. Three specifications of a structural VAR (SVAR) model are estimated to identify an expectations‐driven speculative demand shock. The first includes natural gas inventories, consistently with the theory of storage; the second the risk‐
Christina Anderl   +1 more
wiley   +1 more source

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