Fertility and Early Embryonic Development Toxicity of hzVSF‐v13 in Sprague–Dawley Rats
ABSTRACT Humanized virus suppressing factor–variant 13 (hzVSF‐v13), a monoclonal IgG4 antibody, is a potential therapeutic candidate for COVID‐19. Although fertility and embryonic developmental toxicity studies are crucial for the safety evaluation of new drugs, the toxicological profile of hzVSF‐v13 remains unexplored.
Ji‐Seong Jeong +10 more
wiley +1 more source
Steiner Triple Systems With High Discrepancy
ABSTRACT In this paper, we initiate the study of discrepancy questions for combinatorial designs. Specifically, we show that, for every fixed r ≥ 3 $r\ge 3$ and n ≡ 1 , 3 ( mod 6 ) $n\equiv 1,3\,(\mathrm{mod}\,6)$, any r $r$‐colouring of the triples on [ n ] $[n]$ admits a Steiner triple system of order n $n$ with discrepancy Ω ( n 2 ) ${\rm{\Omega }}({
Lior Gishboliner +2 more
wiley +1 more source
This study found that genetic factors largely influence crying duration and settle ability in infancy, while shared environmental factors primarily affect the number of night wakeups. Etiological influences tended to change from 2 to 5 months, reflecting a highly plastic period in infant brain development and in child‐environment interactions. Abstract
Charlotte Viktorsson +5 more
wiley +1 more source
Cost-effectiveness of apixaban vs. aspirin for the reduction of thrombo-embolism in high-risk patients with device-detected atrial fibrillation: insights from the ARTESiA trial. [PDF]
Lamy A +22 more
europepmc +1 more source
Surface Symphony: Orchestrating DPPC/DOPC Monolayer Behavior
Langmuir trough and atomic force microscopy reveals the physical nature of DPPC and DOPC mixed monolayers. ABSTRACT This study investigates the impact of environmental factors and lipid composition on the structural and morphological properties of DPPC/DOPC (1,2‐Dipalmitoyl‐sn‐glycero‐3‐phosphocholine/1,2‐dioleoyl‐sn‐glycero‐3‐phosphocholine ...
Wisnu Arfian A. Sudjarwo +1 more
wiley +1 more source
Physiological processes induced by different types of physical activity that either oppose or enhance postprandial glucose tolerance. [PDF]
Hamilton MT, Hamilton DG, Zderic TW.
europepmc +1 more source
Are historical trends in weather consistent with model predictions in the Central United States?
Abstract Model projections predict increasing temperatures and precipitation change in many locations in the Central United States. To provide perspective on what these trends might bring relative to what has already happened, we compared historical temperature and precipitation change with what models from the Coupled Model Intercomparison Project ...
Claire Baffaut +8 more
wiley +1 more source
Reducing inappropriate transthoracic echocardiography orders in normotensive patients with acute pulmonary embolism in a community hospital: a quality improvement project. [PDF]
Lee D +4 more
europepmc +1 more source

