Results 221 to 230 of about 3,218,251 (319)

Psilocybin Production With Genetically Modified Aspergillus nidulans Under Pressurized Conditions

open access: yesBiotechnology and Bioengineering, EarlyView.
Shake flask cultures of psilocybin‐producing A. nidulans were investigated with respect to nitrogen source, rheology, power input, and oxygen availability, and subsequently scaled to a stirred tank reactor scale based on specific power input to develop and optimize a pressurized bioprocess.
Sophie Weiser   +7 more
wiley   +1 more source

CRISPR screen reveals SOX2 as a critical regulator of CD133 and cellular stress response in glioblastoma. [PDF]

open access: yesSci Rep
Savage N   +10 more
europepmc   +1 more source

Lab‐Scale Continuous Biomanufacturing: A Tool for Process Development With Adaptive Strategies for Capture and Virus Inactivation

open access: yesBiotechnology and Bioengineering, EarlyView.
Schematic representation of the continuous lab‐scale process. ABSTRACT Monoclonal antibodies (mAbs) are nowadays fundamental in treating a wide range of severe diseases, including cancer, infections, or autoimmune disorders. Due to their high specificity, potent activity, and fewer side effects compared to small molecular drugs, the market for mAbs is ...
Thomas Kruse   +5 more
wiley   +1 more source

Development of a Jacketed Breathable Shake Flask With Process Monitoring, Control, and Bioreactor‐Like Performance

open access: yesBiotechnology and Bioengineering, EarlyView.
This article presents the design and evaluation of a gas‐control jacket integrated with a breathable shake flask, enabling precise regulation of dissolved oxygen and carbon dioxide to improve scalability, process control, and culture performance in shaking bioreactors.
Vikash Kumar   +5 more
wiley   +1 more source

Force stimulation promotes nerve regeneration by restoring cellular energy

open access: yesBMEMat, EarlyView.
Mechanical stimulation can help nerves regenerate in various ways. We developed two devices (a piezo‐motor‐driven stretching device and a SAW‐based actuator) to apply mechanical stimulation to sciatic nerve and DRG neurons. Our study shows that appropriate mechanical force stimulation can promote regeneration by restoring the energy supply to the ...
Zhe Wang   +10 more
wiley   +1 more source

eSLOE 2.0: Examining Data From the First 2 Application Cycles of the Updated Emergency Medicine Electronic Standardized Letter of Evaluation. [PDF]

open access: yesJ Grad Med Educ
Bord S   +7 more
europepmc   +1 more source

A review of the historic and present ecological role of aquatic and shoreline wood, from forest to deep sea

open access: yesBiological Reviews, EarlyView.
ABSTRACT The ecology of forests, their losses, and terrestrial wood decomposition dynamics have been intensively studied and reviewed. In the aquatic realm, reviews have concentrated on large wood (LW) in rivers and the transition from freshwater to marine environments in the Pacific Northwest of North America. However, a comprehensive global synthesis
Jon Dickson   +9 more
wiley   +1 more source

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