Results 11 to 20 of about 193,598 (347)

Inuit youth and environmental research: exploring engagement barriers, strategies, and impacts

open access: yesFACETS, 2022
Community leadership in Arctic environmental research is increasingly recognized as one of many pathways to Indigenous self-determination in Nunavut, Canada.
Hilary Sadowsky   +5 more
doaj   +1 more source

Treatment of Mouse Infants with Amoxicillin, but Not the Human Milk-Derived Antimicrobial HAMLET, Impairs Lung Th17 Responses

open access: yesAntibiotics, 2023
Emerging evidence suggests differential effects of therapeutic antibiotics on infant T cell responses to pathogens. In this study, we explored the impact of the treatment of mouse infants with amoxicillin and the human milk-derived antimicrobial HAMLET ...
Sudhanshu Shekhar   +3 more
doaj   +1 more source

Changes in proteasome structure and function caused by HAMLET in tumor cells. [PDF]

open access: yesPLoS ONE, 2009
Proteasomes control the level of endogenous unfolded proteins by degrading them in the proteolytic core. Insufficient degradation due to altered protein structure or proteasome inhibition may trigger cell death.
Lotta Gustafsson   +5 more
doaj   +1 more source

The Spectre and the Pin: Trompe-l’oeil and Hermeneutic Mourning in Hamnet

open access: yesLitera: Dil, Edebiyat ve Kültür Araştırmaları Dergisi, 2023
The tragic death of Hamnet, son of William Shakespeare, is commonly linked to Hamlet, Prince of Denmark, which is possibly the ghostliest work of tragedy ever penned.
Hatice Karaman, Ayşegül Ernur
doaj   +1 more source

A randomized controlled trial evaluating the impact of selective axillary nerve block after arthroscopic subacromial decompression

open access: yesBMC Anesthesiology, 2020
Background The sensory innervation of the shoulder is complex and there are variations in the branching patterns of the sensory fibres. Articular branches from the axillary nerve to the subacromial bursa are described in more than 50% of investigated ...
Christian Rothe   +6 more
doaj   +1 more source

The human milk protein-lipid complex HAMLET sensitizes bacterial pathogens to traditional antimicrobial agents. [PDF]

open access: yesPLoS ONE, 2012
The fight against antibiotic resistance is one of the most significant challenges to public health of our time. The inevitable development of resistance following the introduction of novel antibiotics has led to an urgent need for the development of new ...
Laura R Marks   +2 more
doaj   +1 more source

The Study of Clinical Application and Anticancer Mechanism of Alpha-lactalbumin and Oleic Acid Composition [PDF]

open access: yesمجله علوم پزشکی صدرا, 2019
Milk protein, alpha-lactalbumin, is one of the proteins that many researchers have done a lot of research on its structure and function. In the late nineties, a completely different activity of α-LA was discovered.
Pooneh Mokarram   +3 more
doaj   +1 more source

The human milk protein-lipid complex HAMLET disrupts glycolysis and induces death in Streptococcus pneumoniae [PDF]

open access: yes, 2019
HAMLET is a complex of human a-lactalbumin (ALA) and oleic acid and kills several Gram-positive bacteria by a mechanism that bears resemblance to apoptosis in eukaryotic cells. To identify HAMLET's bacterial targets, here we used Streptococcus pneumoniae
Hakansson, Anders P.   +3 more
core   +2 more sources

The Significance of Soliloquy as a Literary Technique in Hamlet

open access: yesآداب الكوفة, 2012
In the tragedy of Hamlet by William Shakespeare , there are eleven  soliloquies uttered by the protagonist of the play ''Hamlet'' , king Claudius and Ophelia .
حسين الحسناوي
doaj   +1 more source

Hamlet and The Dervish and Death in the context of the revenge tragedy [PDF]

open access: yesBaština, 2023
This paper tackles researching the tragedy of revenge features in Shakespeare's play Hamlet and Death and the dervish novel by Meša Selimović. This paper aims to demonstrate why the protagonists are (not) the heroes of the revenge tragedy.
Terzić Marija S.
doaj   +1 more source

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