Results 201 to 210 of about 18,476 (288)

Medical pattern classification using a novel binary similarity approach based on an associative classifier. [PDF]

Front Artif Intell
Velazquez-Gonzalez O, Alarcón-Paredes A, Yañez-Marquez C.   +2 more
europepmc   +1 more source

Cannabinoid and adenosine A2A receptor crosstalk regulates postnatal and adult hippocampal neurogenesis

British Journal of Pharmacology, EarlyView.
Background and purpose Adult neurogenesis is a tightly regulated process affected by both cannabinoid receptors (CB1 and CB2) and adenosine 2A (A2A) receptors, both of which modulate neural progenitor cell activity. While emerging evidence suggests an interaction between these neuromodulatory systems, the extent and mechanism of their interplay in ...
Rui S. Rodrigues, Adam Armada‐Moreira, Laura Gómez‐Acero, Filipa F. Ribeiro, Francisco M. Mouro, Ana M. Sebastião, Francisco Ciruela, Ester Aso, Sara Xapelli   +8 more
wiley   +1 more source

Using sequence and cluster analysis to characterize variables that unfold over time: implementation and practical considerations for epidemiologists. [PDF]

Am J Epidemiol
Pacca L, Dang KV, Koenig L, Duarte CDP, Gaye SA, Harrati A, Vable AM.   +6 more
europepmc   +1 more source

Agonist‐specific conformational dynamics at the β2‐adrenoceptor dictate allosteric modulation of Gαs signalling and bronchodilation

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose β2‐adrenoceptor (β2AR) agonists are the cornerstone of asthma therapy and promote bronchodilation through Gαs signalling in airway smooth muscle (ASM), but their efficacy is limited by β‐arrestin‐mediated β2AR desensitization.
Sushrut D. Shah, Joshua Richard, Suvankar Ghosh, Jillian Jerwick, Joice T. Gavali, Raymond B. Penn, Alexander D. MacKerell Jr, Deepak A. Deshpande   +7 more
wiley   +1 more source

ProtDML: label-aware representation learning for broad-spectrum protein function prediction. [PDF]

Brief Bioinform
Kan Y, Yi G.
europepmc   +1 more source

Estimating the total mortality of seabirds following a marine heat wave

Conservation Biology, EarlyView.
Abstract Marine heat waves detrimentally affect a range of marine species, including seabirds, and are increasing in frequency and severity. When thousands of dead seabirds wash up on beaches, the public becomes concerned. However, the number of dead birds recorded on beaches is only a fraction of the total mortality; most birds perish at sea.
Jennifer L. Lavers, William Fulton, Silke Stuckenbrock, Alexander L. Bond   +3 more
wiley   +1 more source

Life‐stage variation in Sable Shearwater (Ardenna carneipes) physiology assessed using proteomics

Ibis, EarlyView.
Life‐stage transitions in seabirds involve substantial shifts in physiological demands, yet the molecular mechanisms underpinning these changes remain poorly resolved. Here we applied untargeted data‐independent acquisition mass spectrometry (DIA‐MS) to characterize and compare the plasma proteomes of fledgling and adult Sable Shearwaters Ardenna ...
Alix M. de Jersey, Alexander L. Bond, Richard Wilson, Graeme R. Zosky, Jack Rivers‐Auty, Jennifer L. Lavers   +5 more
wiley   +1 more source

The neutralizing antibody titer correlate of COVID-19 risk in the COVID-19 variant immunologic landscape (COVAIL) trial was not modified by SARS-CoV-2 amino acid sequence distances. [PDF]

Vaccine
Heng F, Magaret CA, Rouphael NG, Branche AR, Fong Y, Carpp LN, Yu C, Chen S, Zhang B, Diemert DJ, Falsey AR, Graciaa DS, Baden LR, Frey SE, Whitaker JA, Little SJ, Kamidani S, Walter EB, Novak RM, Rupp R, Jackson LA, Babu TM, Kottkamp AC, Luetkemeyer AF, Immergluck LC, Presti RM, Bäcker M, Winokur PL, Mahgoub SM, Goepfert PA, Fusco DN, Atmar RL, Posavad CM, Mu J, Makowski M, Makhene MK, Nayak SU, Simon V, van Bakel H, Roberts PC, Gilbert PB, Coronavirus Variant Immunologic Landscape Trial (COVAIL) Study Team.   +41 more
europepmc   +1 more source

Intercultural Competence Development Through Tourism: A Study of Czech Visitors to France

International Journal of Training and Development, EarlyView.
ABSTRACT This study examines international travel as a context for informal intercultural learning and the development of intercultural competence, aligning with the broader goals of training and development. Using the Cross‐Cultural Adaptability Inventory (CCAI), this research assesses changes in four dimensions—Emotional Resilience, Flexibility ...
Renata Cuhlova, Jiri Nesiba, Prateek Kalia   +2 more
wiley   +1 more source