Results 281 to 290 of about 306,860 (343)

Transmission of bovine H5N1 virus in a hamster model. [PDF]

J Virol
Iwatsuki-Horimoto K, Uraki R, Ito M, Wang T, Guan L, Halfmann P, Eisfeld A, Neumann G, Yamayoshi S, Kawaoka Y.   +9 more
europepmc   +1 more source

Drug development and testing in relation to cell migration and chimerism [PDF]

, 1993
Demetris, AJ, Giorda, R, Murase, N, Starzl, TE, Trucco, M, Valdivia, L   +5 more
core  

Viral‐Directed Augmentation of Kupffer Cell Cross‐Presentation Provokes Antitumor Immunity Against Liver Metastasis

Advanced Science, Volume 12, Issue 39, October 20, 2025.
Targeting Kupffer cells (KC) with a single intravenous infusion of the oncolytic virus VSV‐M51R rather than VSV‐WT induces effective tumor regression in various types of liver metastatic cancers in mice. VSV‐M51R promotes KC proliferation and enhances their antigen cross‐presentation capacity without compromising viability, leading to the induction of ...
Chen Chen, Qing Zhang, Jiajia Li, Xia Zhou, Daxing Gao, Lu Li, Dabing Huang, Jizhou Wang, Zhutian Zeng   +8 more
wiley   +1 more source

Development of a single-nucleotide polymorphism panel genotyping system for genetic analysis of Chinese hamsters. [PDF]

Animal Model Exp Med
Sun M, Guo Y, Ren Z, Song A, Lu J, Li C, Lv J, Guo M, Liu X, Du X, Chen Z, Song G, He Y, Chen Z, Huo X.   +14 more
europepmc   +1 more source

API5 Phosphorylation Promotes Antiviral Immunity by Inhibiting Degradation of Cytosolic RNA Sensor RLRs

Advanced Science, Volume 12, Issue 37, October 6, 2025.
Ubiquitin‐mediated selective autophagy plays a critical role in antiviral innate immunity. The study shows that upon RNA virus infection, cytoplasmic API5 undergoes SRPK1‐dependent phosphorylation at S464, which in turn suppresses p62 K141 ubiquitination‐dependent autophagy.
Tingjuan Deng, Jianan Xu, Linglong Qin, Xingbo Wang, Chenhe Lu, Yanming Huang, Da Liu, Yan Yan, Weiren Dong, Pinglong Xu, Jiyong Zhou   +10 more
wiley   +1 more source

Optimization of a panel of behavioral tests for use in containment using a golden Syrian hamster model. [PDF]

J Virol Methods
Reyna RA, Walker J, Viveros A, Mitchell B, Dulaney E, Shinde DP, Plante JA, Kocsis A, Ntiforo C, Weaver SC, Plante KS.   +10 more
europepmc   +1 more source

Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review

Advanced Science, Volume 12, Issue 38, October 13, 2025.
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu, Jia Yan, Yuyan Zhang, Xiaozhi Ming, Siqi Chen, Zhichao Zou, Nianjie Feng, Jianbo Xiao   +7 more
wiley   +1 more source

Infecting human brain organoids with FFI or sCJD preserves prion traits regardless of host genotype. [PDF]

NPJ Dement
Groveman BR, Foliaki ST, Williams K, Orrù CD, Race B, Zanusso G, Haigh CL.   +6 more
europepmc   +1 more source

Differential effects of age and sex on tau pathology propagation in the htau mouse model: A neuropathological and proteomic study

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Aging is the main risk factor for Alzheimer's disease (AD), acting through still poorly understood mechanisms. AD is associated with the development of a tau pathology, a hallmark lesion propagating in the brain along neuroanatomically connected pathways.
Andreea‐Claudia Kosa, Lidia Lopez‐Gutierrez, Kunie Ando, Emilie Doeraene, Emmanuel Aydin, Hinde Lasri, Alain Wathelet‐Depauw, Karlien Pieters, David Van Morckhoven, Virginie Imbault, Christine Dubois, Xavier Bisteau, Basile Stamatopoulos, Mariana Igoillo‐Esteve, Jean‐Pierre Brion, Karelle Leroy   +15 more
wiley   +1 more source