Results 301 to 310 of about 399,690 (387)

3,3'-Diindolylmethane Improves the Viral Pneumonia Outcomes After Influenza and SARS-CoV-2 Infection in Animal Models. [PDF]

open access: yesViruses
Kiselev V   +11 more
europepmc   +1 more source

UBD‐mediated glycolytic reprogramming promotes M2 macrophage polarization in ovarian cancer immune evasion

open access: yesJournal of Cell Communication and Signaling, Volume 19, Issue 3, September 2025.
Multimodal data analysis reveals the molecular mechanism by which UBD‐mediated glycolytic metabolic reprogramming regulates macrophage polarization and influences immune therapy resistance in OC. Abstract Ovarian cancer (OC) is one of the most common malignant tumors in women, with immunotherapy resistance (ITR) being a major challenge.
Nana Zhang   +4 more
wiley   +1 more source

Recent Developments in the Optical Control of Adrenergic Signaling

open access: yesMedicinal Research Reviews, Volume 45, Issue 5, Page 1307-1322, September 2025.
ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi   +4 more
wiley   +1 more source

Endocardial-to-mesenchymal transition underlies cardiac outflow tract septation and bicuspid aortic valve formation in the Syrian hamster model. [PDF]

open access: yesSci Rep
Soto-Navarrete MT   +5 more
europepmc   +1 more source

Hamster-to-rat liver xenografts protect extrahepatic organs from rejection. [PDF]

open access: yes, 1993
Celli, S   +6 more
core  

Embedding Coaching and Local Education Champions in Implementing Trauma Informed Practice

open access: yesPsychology in the Schools, Volume 62, Issue 9, Page 3285-3301, September 2025.
ABSTRACT Growing recognition of the high prevalence of childhood adversity and maltreatment in the general population has led to efforts to support students through trauma‐informed practice (TIP). This study investigated the use of coaching in effectively implementing trauma‐informed programs in schools.
Govind Krishnamoorthy   +11 more
wiley   +1 more source

De-coupling immune parameters and toxicity associated with IL-12 agonism. [PDF]

open access: yesCell Rep
Lanzar ZR   +12 more
europepmc   +1 more source

Functional Differences Between SIRPα Splice Isoforms

open access: yesGenes to Cells, Volume 30, Issue 5, September 2025.
SIRPα is expressed in phagocytic cells, and when it recognizes CD47, “don't eat me” signal, it suppresses phagocytosis. We show here that short SIRPα, a less‐studied splice isoform, has a different function from a well‐studied long SIRPα. Short SIRPα may act as a “don't eat me” signal regulator.
Mihoko Kajita   +10 more
wiley   +1 more source

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