3,3'-Diindolylmethane Improves the Viral Pneumonia Outcomes After Influenza and SARS-CoV-2 Infection in Animal Models. [PDF]
Kiselev V+11 more
europepmc +1 more source
Successful hamster-to-rat liver xenotransplantation under fk506 immunosuppression induces unresponsiveness to hamster heart and skin [PDF]
Celli, S+5 more
core
Multimodal data analysis reveals the molecular mechanism by which UBD‐mediated glycolytic metabolic reprogramming regulates macrophage polarization and influences immune therapy resistance in OC. Abstract Ovarian cancer (OC) is one of the most common malignant tumors in women, with immunotherapy resistance (ITR) being a major challenge.
Nana Zhang+4 more
wiley +1 more source
Recent Developments in the Optical Control of Adrenergic Signaling
ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi+4 more
wiley +1 more source
Endocardial-to-mesenchymal transition underlies cardiac outflow tract septation and bicuspid aortic valve formation in the Syrian hamster model. [PDF]
Soto-Navarrete MT+5 more
europepmc +1 more source
Hamster-to-rat liver xenografts protect extrahepatic organs from rejection. [PDF]
Celli, S+6 more
core
Embedding Coaching and Local Education Champions in Implementing Trauma Informed Practice
ABSTRACT Growing recognition of the high prevalence of childhood adversity and maltreatment in the general population has led to efforts to support students through trauma‐informed practice (TIP). This study investigated the use of coaching in effectively implementing trauma‐informed programs in schools.
Govind Krishnamoorthy+11 more
wiley +1 more source
De-coupling immune parameters and toxicity associated with IL-12 agonism. [PDF]
Lanzar ZR+12 more
europepmc +1 more source
Functional Differences Between SIRPα Splice Isoforms
SIRPα is expressed in phagocytic cells, and when it recognizes CD47, “don't eat me” signal, it suppresses phagocytosis. We show here that short SIRPα, a less‐studied splice isoform, has a different function from a well‐studied long SIRPα. Short SIRPα may act as a “don't eat me” signal regulator.
Mihoko Kajita+10 more
wiley +1 more source