Results 311 to 320 of about 399,690 (387)

Infectivity studies of Leishmania (Leishmania) infantum chagasi isolated from non-ulcerated cutaneous leishmaniasis. [PDF]

Rev Inst Med Trop Sao Paulo
Araujo Flores GV, Sandoval Pacheco CM, Tomokane TY, Sosa Ochoa WH, Silveira FT, Zúniga C, Pereira Corbett CE, Soares RPP, Passero LFD, Laurenti MD.   +9 more
europepmc   +1 more source

Pharmacological Inhibition of c‐Jun N‐Terminal Kinase Activity Exacerbates Liver Damage in Schistosoma mansoni Infected Mice

Liver International, Volume 45, Issue 9, September 2025.
ABSTRACT Background and Aims Schistosomiasis is a neglected tropical disease affecting more than 250 million people worldwide. Eggs of the parasitic helminth S. mansoni cause major morbidity in the liver, spleen and intestine. Of note, egg‐released soluble antigens (SEA) induce the transcription factor c‐Jun in hepatocytes, promoting hepatocellular ...
Frederik Stettler, Lukas Knedla, Maximilian Hagen, Verena von Bülow, Heike Müller, Annette Tschuschner, Daniel Zahner, Simone Haeberlein, Max F. Moescheid, Anita Windhorst, Monika Burg‐Roderfeld, Dieter Glebe, Bernardo Pereira Moreira, Céline Lesieur, Andreas Schmid, Franco H. Falcone, Christoph G. Grevelding, Elke Roeb, Martin Roderfeld   +18 more
wiley   +1 more source

Azole resistance in <i>Aspergillus</i> isolates from animals or their direct environment (2013-2023): a systematic review. [PDF]

Front Vet Sci
Dieste-Pérez L, Holstege MMC, de Jong JE, Heuvelink AE.   +3 more
europepmc   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, Volume 599, Issue 15, Page 2167-2178, August 2025.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

Unpredictable warm spells in winter increase blood cortisol level but lengthen telomeres in a seasonal rodent <i>Phodopus sungorus</i>. [PDF]

Proc Biol Sci
Kletkiewicz H, Kowalski K, Kęsy J, Trzeciak P, Nowak A, Jefimow M, Przybylska-Piech A.   +6 more
europepmc   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, Volume 19, Issue 8, Page 2196-2211, August 2025.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Comparative transcriptomics in serial organs uncovers early and pan-organ developmental changes associated with organ-specific morphological adaptation. [PDF]

Nat Commun
Sémon M, Mouginot M, Peltier M, Corneloup C, Veber P, Guéguen L, Pantalacci S.   +6 more
europepmc   +1 more source

Biosecurity Primitive: Polymerase X‐based Genetic Physical Unclonable Functions

Advanced Science, Volume 12, Issue 29, August 7, 2025.
What if every cell line can carry an unforgeable genomic fingerprint—one that proves its origin, ensures its authenticity, and thwarts unauthorized duplication? Here, CRISPR‐induced DNA lesions paired with TdT‐mediated repair produce robust, unique, and unclonable genetic signatures—advancing the concept of molecular Physical Unclonable Functions (PUF)
Zikun Zhou, Taek Kang, Jie Chen, Yesh Doctor, Jocelyn G Camposagrado, Yiorgos Makris, Alexander Pertsemlidis, Leonidas Bleris   +7 more
wiley   +1 more source

Leptospirosis in Unconventional Mammal Pets. [PDF]

Vet Sci
Bertelloni F, Ebani VV.
europepmc   +1 more source

Antifibrotic effects of specific targeting of the 5‐hydroxytryptamine 2B receptor (5‐HT2BR) in murine models and ex vivo models of scleroderma skin

Arthritis &Rheumatology, Volume 77, Issue 8, Page 1063-1076, August 2025.
Objective Systemic sclerosis (SSc) is a connective tissue disease with fibrotic remodeling of the skin and various internal organs. SSc is associated with the highest case‐specific mortality of all rheumatic autoimmune diseases with limited antifibrotic treatment options.
Thuong Trinh‐Minh, Cuong Tran‐Manh, Andrea‐Hermina Györfi, Nicholas Dickel, Christoph Liebel, Xiang Zhou, Jiucun Wang, Meik Kunz, Helena Arozenius, Lars Pettersson, Sam Lindgren, Christina Wenglén, Jörg H. W. Distler   +12 more
wiley   +1 more source