Results 201 to 210 of about 34,360 (284)

Safety and pharmacokinetics of anumigilimab for hidradenitis suppurativa or palmoplantar pustulosis: A phase 1b study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Anumigilimab, a novel anti‐G‐CSF receptor antibody, was investigated in a phase 1b trial involving 39 patients with hidradenitis suppurativa or palmoplantar pustulosis. No serious safety concerns related to anumigilimab were noted, and PK and PD were dose dependent.
Johannes S. Kern, Simon Francis Thomsen, Georgios Kokolakis, Maurizio Podda, Gregor B. E. Jemec, Kurt Gebauer, Claus Zachariae, John Frew, Pablo Fernandez‐Peñas, Falk G. Bechara, Stefan Beissert, Sourabh Malandkar, Karen Scalzo‐Inguanti, Partha Nandy, Selvakumar Sukumar   +14 more
wiley   +1 more source

Interactive and joint effects of multiple meteorological and air pollution exposures on hand, foot and mouth disease risk in western China: a time-series analysis. [PDF]

BMJ Public Health
Sun J, Tang H, Jing G, Wu Y, Chang Y, Chen J, Zhang W, Du Z, Hao Y.   +8 more
europepmc   +1 more source

Tooth Sensitivity, Bleaching Efficacy, and Quality of Life in Young People and Adults: A Stratified, Randomized Bi‐Center Study

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objectives This study compared tooth sensitivity, bleaching efficacy, and the impact on oral health‐related quality of life between at‐home and in‐office tooth bleaching in adults and young individuals. Materials and Methods Eighty participants, 40 young people (14–20 years) and 40 adults (40–60 years), were randomly assigned to receive either
Sirley Raiane Mamede Veloso, Sheyla Mamede Veloso, Jamile Menezes de Souza, Eduardo Bresciani, Taciana Marco Ferraz Caneppele, Gabriela Queiroz de Melo Monteiro   +5 more
wiley   +1 more source

Shifting epidemiological patterns and strain replacement of hand, foot, and mouth disease in southern China, 2009-2022: A longitudinal study. [PDF]

PLoS One
Hou Y, Chen H, Jiang Y, Huang H, Tan Z, Nehl EJ, Li H, Wang J, He J, Zhong C, Wang Y, Xiao J, Chen M, Zheng Z.   +13 more
europepmc   +1 more source

Immune effector cell‐associated neurotoxicity syndrome (ICANS) during tebentafusp in metastatic uveal melanoma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Laura Schreieder, Laura Jockel, Veronika Zenderowski, Ralf A. Linker, Sebastian Haferkamp, Elisabeth Bumes, Peter Hau, Konstantin Drexler   +7 more
wiley   +1 more source

Elevated Nocturnal CO2 and Autonomic Dysfunction in Children With Down Syndrome

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Sleep‐disordered breathing (SDB) frequently complicates Down syndrome (DS). Beyond upper airway obstruction, emerging evidence suggests an autonomic nervous system (ANS) dysfunction affecting CO2 regulation. The aim of this study was to investigate nocturnal gas exchanges in children with DS and compare them to what has been ...
Jessica Taytard, Segolène Falquero, Sophie Denamur, Pierre‐Yves Boelle, Karl Leroux, Harriet Corvol, Aimé Ravel, Clotilde Mircher, Jeanne Toulas, Emmanuelle Prioux, Marie‐Anne Caillaud, Guillaume Aubertin, Hervé Walti   +12 more
wiley   +1 more source

LINC1467 Activates the IPO8-p65 Axis to Restrict Hand, Foot, and Mouth Disease Virus Replication. [PDF]

Pathogens
Zhang X, Li J, Ding L, Zhang J, Yang F, Luo Y, Chen W.   +6 more
europepmc   +1 more source

Experience in action: Using art‐science activities to explore experiences of movement and the body in Parkinson's and autism

Journal of Neuropsychology, EarlyView.
Abstract To explore possible new directions for sensorimotor research, we created experiential workshops for people with lived experience. Seven people with Parkinson's and six older autistic adults attended artist‐led drop‐in art‐science workshops, designed with advisors with lived experience.
Ellen Poliakoff, Antony Hall, Eve Edmonds, Peter Baimbridge, Gary Copitch, Graham Hanks, Matthew Sullivan, Emma Gowen   +7 more
wiley   +1 more source

Reimagining Interdisciplinarity: Sensitization, Reflexivity, and Mobilization Across Landscapes of Practice

Journal of Management Studies, EarlyView.
Abstract Interdisciplinary research (IDR) is widely promoted as essential for addressing complex societal challenges, yet its enactment remains fraught. We argue that dominant typological and structural approaches miscast IDR and underplay the practical work through which it unfolds.
Ryan Nolan, Frank Siedlok, Paul Hibbert
wiley   +1 more source

Standardized neutralizing antibody assay for Coxsackievirus A10 in clinical trial: A framework for multivalent hand, foot, and mouth disease vaccine evaluation. [PDF]

Hum Vaccin Immunother
Wang Q, Li L, Gao J, Liu M, Wang Y, He Q, Wang W, Li Y, Gu M, Xie Z, Liu Q, Han J, Zhang Z, Guo J, Wu X, Mao Q, Chen X, Liang Z, Gao F, Ma X.   +19 more
europepmc   +1 more source