Results 121 to 130 of about 6,416 (219)

Circulating Salivary miRNA hsa-miR-221 as Clinically Validated Diagnostic Marker for Hand, Foot, and Mouth Disease in Pediatric Patients

open access: yesEBioMedicine, 2018
Enhancements in the diagnostic capabilities using host biomarkers are currently much needed where sensitivity and specificity issues plague the diagnosis of Hand, Foot and Mouth Disease (HFMD) in pediatrics clinical samples.
Nyo Min   +7 more
doaj   +1 more source

Towards cross-lingual alerting for bursty epidemic events [PDF]

open access: yes, 2011
Background: Online news reports are increasingly becoming a source for event based early warning systems that detect natural disasters. Harnessing the massive volume of information available from multilingual newswire presents as many challenges as ...
Collier, Nigel
core   +5 more sources

A Hand-Foot-and-Mouth Disease Outbreak in an Atypical Population of College Students

open access: yesJournal of Primary Care & Community Health
Hand-foot-and-mouth disease (HFMD), which is typically seen in the younger pediatric population, is uncommon in older adolescent and young adult populations. We report on an atypical outbreak of HFMD among college students at a mid-size university in the
Nancy G. Russell, Roanna Kessler
doaj   +1 more source

Improving the inhibitors targeting enterovirus 71 3C proteinase [PDF]

open access: yes, 2015
手足口病(HFMD)的频繁爆发,给许多婴幼儿带来痛苦甚至导致死亡。目前,没有任何疫苗和抗病毒治疗可用于预防和治疗手足口病。肠道病毒71型(EV71)是引起手足口病的主要病原体,它能够侵入中枢神经系统引起严重的后遗症。3C蛋白酶是EV71病毒复制过程中的一个重要蛋白酶,在EV71的成熟过程和拮抗宿主细胞的先天性免疫反应中有着重要作用。因此,EV713C蛋白酶是一个很好的抗EV71药物靶点。 AG7088最先是针对人病毒3C蛋白酶进行设计的,已被证实可有效抑制EV71病毒活性 ...
吴彩明
core  

Compartmental Modeling of Hand, Foot and Mouth Infectious Disease (HFMD) [PDF]

open access: yesResearch Journal of Applied Sciences, 2010
Nandita Roy, Nilimesh Halder
openaire   +1 more source

Unilateral acute idiopathic maculopathy related to hand–foot–mouth disease: Case report and literature review

open access: yesTaiwan Journal of Ophthalmology
Unilateral acute idiopathic maculopathy (UAIM) is a rare disease that may cause unilateral vision loss in young adults after a flu-like illness. Occasionally, it is associated with hand–foot–mouth disease (HFMD) and is often underdiagnosed.
Chu-Yu Yen, I-Mo Fang
doaj   +1 more source

Hand, Foot, and Mouth Disease in China: critical community size and spatial vaccination strategies

open access: yes
Hand Foot and Mouth Disease (HFMD) constitutes a considerable burden for health care systems across China. Yet this burden displays important geographic heterogeneity that directly affects the local persistence and the dynamics of the disease, and thus ...
Chang, Zhaorui   +12 more
core   +1 more source

Development of novel miRNA-based vaccines and antivirals against Enterovirus 71 [PDF]

open access: yes, 2016
The Hand, Foot and Mouth Disease (HFMD) is caused by Enterovirus 71 (EV-A71) and Coxsackie viruses. Common HFMD symptoms are high fever (≥ 39oC), rashes, and ulcers but complications due to virulent EV-A71 may arise leading to cardiopulmonary failure and
Poh, Chit Laa *, Yee, Isabel Pin Tsin *
core  

The Nucleocapsid Protein Of Newcastle Disease Virus As A Carrier For The Vp1 Polypeptides Of Enterovirus 71 [PDF]

open access: yes, 2005
Human enterovirus 71 (EV71) is an important human enterovirus which belongs to the Enterovirus genus of the Picornaviridae family. Large outbreaks of EV71 have been associated with severe central nervous disease (CNS) manifestations including the hand,
Sivasamugham, Lalita Ambigal
core  

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