Results 71 to 80 of about 6,416 (219)

Threshold dynamics of an age-structured HFMD model

open access: yesXi'an Gongcheng Daxue xuebao, 2021
Given the transmission of hand-foot-mouth disease (HFMD) is related to the age structure of the host, an age-structured model for the disease transmission dynamics of HFMD is formulated and analyzed.
Junli LIU, Bairu LIU, Pan LYU
doaj   +1 more source

Human enterovirus 71 epidemics: what's next? [PDF]

open access: yes, 2013
published_or_final_versio
Lau, SKP, Woo, PCY, Yip, CY, Yuen, KY
core   +1 more source

Targeting WDPF domain of Hsp27 achieves a broad spectrum of antiviral

open access: yesMedComm, Volume 6, Issue 3, March 2025.
Ser78 phosphorylation of Hsp27 plays an important role in Hsp27 nuclear translocation, which induces hnRNP A1 cytosol relocation and further enhances the IRES activity and viral replication mediated by EV‐A71 2Apro. Hsp27‐derived WDPF peptide competitively inhibited Hsp27 phosphorylation on serine 78 to block Hsp27/hnRNP A1 translocation and further ...
Mandi Wu   +9 more
wiley   +1 more source

The Fecal Virome of Children with Hand, Foot, and Mouth Disease that Tested PCR Negative for Pathogenic Enteroviruses. [PDF]

open access: yesPLoS ONE, 2015
Hand, foot, and mouth disease (HFMD) affects infant and young children. A viral metagenomic approach was used to identify the eukaryotic viruses in fecal samples from 29 Thai children with clinical diagnosis of HFMD collected during the 2012 outbreak ...
Piyada Linsuwanon   +5 more
doaj   +1 more source

Knowledge and preventive practices on hand foot and mouth disease among caregivers in two barangays in Mandurriao, Iloilo City [PDF]

open access: yes, 2017
onlyThis study was conducted to determine the knowledge and preventive practices against Hand Foot and Mouth Disease (HFMD) among caregivers of 0-6 children in selected barangays in Iloilo City.
Depasupil, Mon Ryann Deloso
core  

Suspected Hand, Foot and Mouth Disease (HFMD) in an Adult: An Uncommon but Important Infectious Disease

open access: yesJournal of Clinical and Health Sciences, 2020
Hand, foot and mouth disease (HFMD) is an uncommon infection to be diagnosed in adults. We present a case of a 32-year-old immunocompetent man with HFMD. This case report highlights the importance of identifying a common childhood disease that could occur in an adult.
Ilham Ameera Ismail, Khasnur Abd Malek
openaire   +1 more source

In Vitro Discovery of a Therapeutic Lead for HFMD From a Library Screen of Rocaglates/Aglains

open access: yesJournal of Medical Virology, Volume 97, Issue 2, February 2025.
ABSTRACT The lack of effective antiviral treatments for enteroviruses, including human enterovirus A71 (EV‐A71), have resulted in an immense global healthcare burden associated with hand‐foot‐and‐mouth disease (HFMD). Rocaglates and aglains belong to a family of compounds produced by Aglaia genus plants.
Adrian Oo   +10 more
wiley   +1 more source

Risk factors for neurogenic pulmonary edema in patients with severe hand, foot, and mouth disease: A meta-analysis

open access: yesInternational Journal of Infectious Diseases, 2017
Objective: To investigate the risk factors for neurogenic pulmonary edema (NPE) in patients with severe hand, foot, and mouth disease (HFMD) and to provide evidence for the prevention and treatment of NPE.
Lijun Peng, Ruping Luo, Zhisheng Jiang
doaj   +1 more source

Development of novel vaccines against Enterovirus-71 [PDF]

open access: yes, 2015
The hand, foot and mouth disease is caused by a group of Enteroviruses such as Enterovirus 71 (EV-A71) and Coxsackievirus CV-A5, CV-A8, and CV-A16. Mild symptoms of EV-A71 infection in children range from high fever, vomiting, rashes and ulcers in mouth
Poh, Chit Laa *, Yee, Isabel Pin Tsin *
core   +2 more sources

EV71 vaccine, a new tool to control outbreaks of hand, foot and mouth disease (HFMD)

open access: yesExpert Review of Vaccines, 2016
On December 3rd 2015, the China Food and Drug Administration (CFDA) approved the first inactivated Enterovirus 71 (EV71) whole virus vaccine for preventing severe hand, foot and mouth disease (HFMD). As one of the few preventive vaccines for children's infectious diseases generated by the developing countries in recent years, EV71 vaccine is a blessing
Qun-ying, Mao   +4 more
openaire   +2 more sources

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