FEBS Open Bio, EarlyView.Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy +14 more
wiley +1 more source
AttentionHand: Text-driven Controllable Hand Image Generation for 3D Hand Reconstruction in the Wild [PDF]
arXivRecently, there has been a significant amount of research conducted on 3D hand reconstruction to use various forms of human-computer interaction. However, 3D hand reconstruction in the wild is challenging due to extreme lack of in-the-wild 3D hand datasets.
arxiv
XVII. Information, that a further publication of the late Mr. Smeaton's engineery designs and papers is in hand.—copy of a list of the principal British strata, by the late Rev. John Michel, (of whose posthumous papers on geological subjects, further information is requested;)—with some experiments of Mr. Smeaton's on limestones,—and queries respecting Mr. Tofield [PDF]
John Farey
openalex +1 more source
Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding
FEBS Open Bio, EarlyView.The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla +4 more
wiley +1 more source
Stielers Hand-Atlas : 100 Karten in Kupferstich mit 162 Nebenkarten /
, 1907 Adolf Stieler, C. Vogel
openalex +2 more sources
Mapping Hsp104 interactions using cross‐linking mass spectrometry
FEBS Open Bio, EarlyView.This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal +3 more
wiley +1 more source
A potential biomarker of cognitive impairment: The olfactory dysfunction and its genes expression
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1884-1897, December 2022., 2022 Abstract Objective Accumulation evidence has reported that olfactory impairment may be an essential clinical marker and predictor of mild cognitive impairment or Alzheimer's disease. Method Participants were enrolled in the population‐based, prospective study in Fuxin county, Liaoning province, China between 2019 and 2021.
Jiayi Song +11 more
wiley +1 more source
Illuminating the Proximal Phalanx: Revisiting Osseous Perfusion by Micro-computed Tomography
Plastic and Reconstructive Surgery, Global Open, 2022 Andrew Abadeer, MD +5 more
doaj +1 more source
Two Hands Are Better Than One: Resolving Hand to Hand Intersections via Occupancy Networks [PDF]
arXiv3D hand pose estimation from images has seen considerable interest from the literature, with new methods improving overall 3D accuracy. One current challenge is to address hand-to-hand interaction where self-occlusions and finger articulation pose a significant problem to estimation.
arxiv