Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Illuminating the Proximal Phalanx: Revisiting Osseous Perfusion by Micro-computed Tomography
Andrew Abadeer, MD +5 more
doaj +1 more source
V. Researches on the structure, organization, and classification of the fossil reptilia.—III. On parts of the skeleton of a mammal from Triassic rocks of Klipfontein, Fraserberg, South Africa (theriodesmus phylarchus, seeley), illustrating the reptilian inheritance in the mammalian hand [PDF]
H. G. Seeley
openalex +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
The effect of body posture on the hand blood flow [PDF]
Peter Beaconsfield, Jean Ginsburg
openalex +1 more source
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Hand-Schüler-Christian Disease Treated with Cortisone
Robert H. Sewell
openalex +1 more source
Two Cases of Hand-Schuller-Christian Disease in Infancy [PDF]
Florence Nash, John Cavanagh
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source

