Results 141 to 150 of about 14,131,417 (354)

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Hemorrhage and thrombosis hand in hand

Annals of Saudi Medicine, 2012
Ashish Bhalla, Paramjeet Singh, Niranjan Khandelwal, Goto Karlo, Sameer Vyas   +4 more
openaire   +4 more sources

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

OCCUPATION NEURITIS OF THE DEEP PALMAR BRANCH OF THE ULNAR NERVE A WELL DEFINED CLINICAL TYPE OF PROFESSIONAL PALSY OF THE HAND [PDF]

, 1908
J. Ramsay Hunt
openalex   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Advanced Nanoparticle-Engineered Platforms for Peripheral Nerve Repair: Multimodal Therapeutic Strategies and Clinical Translation

International Journal of Nanomedicine
Shaoyan Shi,1 Xingxing Yu,2 Xuehai Ou,1 Changming Zheng,1 Fei Xie,1 Yansheng Huang3 1Department of Hand Surgery, Honghui Hospital, Xi’an Jiaotong University, Xi’an, Shaanxi, 710000, People’s Republic of China; 2Department of Laboratory Medicine, Xi’ an ...
Shi S, Yu X, Ou X, Zheng C, Xie F, Huang Y   +5 more
doaj  

SALVAGE OF THE HAND BY TIMELY BEPARATIVE SURGERY [PDF]

, 1919
John B. Roberts
openalex   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Crô Magnon Man: Imprints of his Hand

, 1914
W. J. Sollas
openalex   +1 more source

Access to early childhood education in Australia [PDF]

This report presents AIFS research undertaken to identify gaps in access to and participation in preschool programs by Australian children in the year before full-time school review how "access" to preschool services is conceptualised and defined ...
Jennifer Baxter, Kelly Hand
core