Results 171 to 180 of about 14,131,417 (354)

Key role for inhibins in effective T cell activation, migration and Th17 differentiation

open access: yesFEBS Open Bio, EarlyView.
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco   +5 more
wiley   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

Testing and Proving, Hand-in-Hand

open access: yes, 2010
The motivating ideal of my lifetime’s scientific research has been that of program correctness, achieved with the aid of mathematical proof. As suggested by Turing, Floyd, and others, the proofs would be based on the decoration of a program with assertions, that would be proved true if ever they were evaluated at the point where they were written in ...
openaire   +3 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Unraveling the mystery of alien hand syndrome: when your hand has a mind of its own. [PDF]

open access: yesOrphanet J Rare Dis
Moghib K   +8 more
europepmc   +1 more source

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