Results 81 to 90 of about 14,434,144 (306)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Reconstructive Surgery for Zone 5 Closed Rupture of the Flexor Tendons of the Ulnar Three Fingers: Three Case Reports

Case Reports in Orthopedics
Three older patients with closed ruptures of the flexor tendons of three ulnar fingers, resulting from distal radius malunion, underwent reconstructive surgeries using either free tendon grafts or extensor carpi radialis longus tendon transfers.
Takuma Kuroda, Koji Moriya, Hisao Koda, Naoto Tsubokawa, Yutaka Maki   +4 more
doaj   +1 more source

Hand [PDF]

BMJ, 2005
Otto, Chan, Tudor, Hughes
openaire   +2 more sources

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

The Application of Sesamoid Position in Diagnosing Thumb Metacarpophalangeal Joint Dorsal Dislocation: A Retrospective Study

Orthopaedic Surgery
Objectives The position of sesamoid of thumb metacarpophalangeal (MCP) joint changed clearly when the joint was dislocated dorsally. However, the significance of sesamoid location in diagnosing joint dislocation was unclear.
Jianhua Xu, Li Han, Bo Zhang, Shuming Cao, Dake Zhu, Zhonggang Yin, Ketong Gong, Haihua Zhan   +7 more
doaj   +1 more source

Rejoinder: Classifier Technology and the Illusion of Progress

, 2006
Rejoinder: Classifier Technology and the Illusion of Progress [math.ST/0606441]Comment: Published at http://dx.doi.org/10.1214/088342306000000079 in the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics ...
Hand, David J.
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Hands [PDF]

Intensive Care Medicine, 2020
openaire   +2 more sources

Are encalves amenities? An empricial investigation in the Southwest United States. [PDF]

The role of linguistic enclaves in wage determination is investigated for immigrants and non-immigrants. It is hypothesized that enclaves could affect wages positively as an aid to immigrant adjustment, or negatively as an amenity that minority language ...
Michael Hand
core