Results 181 to 190 of about 2,792,025 (292)

Response to: Interosseous Membrane Reconstruction With Suture Button for Essex-Lopresti Fracture and Lateral Collateral Ligament Complex Rupture Leading to Rerupture of the Ligament and Radial Head Dislocation. [PDF]

J Hand Surg Glob Online
Heifner JJ, Orbay JL.
europepmc   +1 more source

Mn/Zn Bimetallic MOF‐Integrated Hydrogel Alleviates Excessive Mitochondrial Fission in BMSCs to Promote Osteoporotic Jawbone Repair

Advanced Science, EarlyView.
Excessive reactive oxygen species (ROS) and chronic inflammation impair bone marrow‐derived mesenchymal stem cells (BMSCs), contributing to poor healing in osteoporotic jawbone defect. The gelatin methacryloyl hydrogel loaded with manganese‐doped zeolitic imidazolate framework (Mn‐ZIF‐8@GelMA) promotes regeneration through redox regulation and ...
Xiayue Jin, Shengjia Ye, Yun Yuan, Xueying Yang, Jiarui Cui, Hongming Zhang, Hui Huang   +6 more
wiley   +1 more source

The use of low-intensity pulsed ultrasound for the treatment of established nonunion fractures: A systematic review and meta-analysis. [PDF]

Medicine (Baltimore)
Côté-Picard C, Dupuis F, Gagnon M, Côté AA, Ducharme É, Lantier P, Morin M, Massé-Alarie H.   +7 more
europepmc   +1 more source

NCLX Inhibition plus Ca2+ Delivery Potentiates Electroporation and Antitumor Immunity in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Chuanbing Zhao, Long He, Yu Lu, Zanglong Deng, Hongzhen Wei, Yunpeng Zhang, Ming Yang, Tao Yin   +7 more
wiley   +1 more source

Osteoblastoma of the Hamate: A Case Report. [PDF]

J Orthop Case Rep
Kantiwal P, Adnan SM, Chawla S, Suhail A, Sharma R, Aggarwal D.   +5 more
europepmc   +1 more source

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

Advanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao, Zhangrong Cheng, Xianglong Chen, Wenbo Wu, Wang Wu, Zimu Yu, Cao Yang, Yukun Zhang   +7 more
wiley   +1 more source

Decoupling Stable Cyclic Deformation From Defect Accumulation in Metals

Advanced Science, EarlyView.
Introducing amorphous nanoparticles into a metal matrix enables a cyclic deformation regime where strain hardening and defect accumulation are decoupled. These nanoparticles act as dislocation sinks and undergo reversible shear transformations, sustaining microstructural stability over millions of cycles.
Chenjun Ye, Shaofan Ge, Tian Yang, Leyi Tang, Kang Wang, Y. Morris Wang, Jun Ding, Zan Li, Di Zhang, En (Evan) Ma   +9 more
wiley   +1 more source

Avascular necrosis of the sesamoid bone of the second metacarpophalangeal joint - a literature review and therapy recommendations. [PDF]

GMS Interdiscip Plast Reconstr Surg DGPW
Nicklas A, Dragu A, Bienger K.
europepmc   +1 more source

A Biomimetic PLK1 Nanodelivery System Promotes Migrasome‐Mediated Mitocytosis to Restore Efferocytosis and Functional Recovery After Spinal Cord Injury

Advanced Science, EarlyView.
MM‐NPs@PLK1 are formed by encapsulating PLK1 plasmids within CBP5 and coating the nanocomplexes with macrophage membranes. After macrophage‐associated uptake, the NPs@PLK1 enter the cytoplasm and release the PLK1‐encoding plasmid in response to elevated intracellular ROS levels.
Zhenxin Hu, Haoli Wang, Jing Huang, Junhua Zhou, Jialong Hou, Hanwei Miao, Huixin Tan, Yining Wang, Hao Hu, Na Li, Pengcheng Qiu, Hongyu Zhang, Da He, Qingqing Wang   +13 more
wiley   +1 more source