Results 71 to 80 of about 5,331 (215)

Dermatologic Toxicities Associated With Novel Pan‐RAS/RAF Inhibitors

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background The mitogen‐activated protein kinase (MAPK) pathway plays a key role in cell‐cycle regulation and tumor progression in cancer. Dermatologic toxicities (DTs) to newer pan‐RAS (RMC‐6236) and pan‐RAF (LXH254/naporafenib) inhibitors are emerging.
Lin J. He, Shaymaa Hegazy, Phyu P. Aung, Priyadharsini Nagarajan, Fiorinda Muhaj, Adrienne N. Choksi, Ana M. Ciurea, Kelly C. Nelson, Doina Ivan, Carlos A. Torres‐ Cabala, Victor G. Prieto, Jonathan L. Curry   +11 more
wiley   +1 more source

PAINFUL AND ITCHY DERMATOSES CARRY THE HIGHEST PSYCHOLOGICAL BURDEN FOR DERMATOVENEREOLOGICAL PATIENTS

, 2021
Background: Most dermatovenereological diseases are not life-threatening but nevertheless are highly prevalent disorders. Psychosocial aspects of skin diseases and physical symptoms strongly influence patient's quality of life (QoL) which results in ...
Situm, Mirna, Juras, Josip, Bulat, Vedrana, Stugnetic, Tomo, Dediol, Iva, Tomljenovic, Dean, Buljan, Marija   +6 more
core  

Validation of the German version of Infants and Toddlers Dermatology Quality of Life (InToDermQoL) Questionnaire

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Skin diseases can greatly impair quality of life (QoL) of pediatric patients and their families. The Infants and Toddlers Dermatology Quality of Life questionnaire (InToDermQoL) is the first skin‐generic instrument assessing QoL in children ≤ 4 years, as reported by their caregiver. This study aimed to psychometrically
Juliane Traxler, Neuza da Silva Burger, Matthias Augustin, Hagen Ott, Sanna Hoffmann, Regina Fölster‐Holst, Maria Baumeister, Petra Staubach, Rachel Sommer   +8 more
wiley   +1 more source

Paquidermodactilia transgressiva: relato de um caso Transgrediens pachydermodactyly: report of a case

Anais Brasileiros de Dermatologia, 2009
A paquidermodactilia é forma rara de fibromatose digital envolvendo as porções proximais dos dedos, que afeta homens jovens. Apresenta-se caso de paciente de 25 anos com quadro de nódulos assintomáticos nas mãos há dois anos, e há três meses com lesões ...
Lia Rachel Gomes do Vale, Flávia Regina Coeli, Nilceo Michalany, Karime Marques Hassun, Adriana Maria Porro   +4 more
doaj   +1 more source

A review of skin microbiome and new challenges to cosmetic microbiome‐friendly formulations

International Journal of Cosmetic Science, EarlyView.
Microbiome‐friendly concepts offer new perspectives for a healthy relationship between cosmetic use and the skin microbiome, especially the interaction of non‐biotic cosmetic ingredients with the skin, requiring further studies to clarify the dynamics between the skin microbiome and different classes of cosmetic ingredients.
Yasmin Rosa Santos, Newton Andréo‐Filho, Patricia Santos Lopes, Vânia Rodrigues Leite‐Silva   +3 more
wiley   +1 more source

Hand eczema

, 2008
Das Handekzem ist ein sehr häufiges und weit verbreitetes Krankheitsbild. Vermutlich wurde es zum ersten mal im neunzehnten Jahrhundert beschrieben. Die sozioökonomischen Auswirkungen sind enorm, was sich vor allem mit der hohen Inzidenz und Prävalenz ...
Guttmann, Oliver
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The pH of the skin surface and its impact on the barrier function [PDF]

, 2006
The `acid mantle' of the stratum corneum seems to be important for both permeability barrier formation and cutaneous antimicrobial defense. However, the origin of the acidic pH, measurable on the skin surface, remains conjectural.
Korting, Hans Christian, Schmid-Wendtner, M.-H.   +1 more
core   +1 more source

Lichen striatus with onychodystrophy on a finger. Case report

Przegląd Dermatologiczny, 2016
Introduction . Lichen striatus (LS) is a benign, self-limited, inflammatory dermatosis of unknown etiology, which mainly affects children. It manifests as flat brownish papules with linear distribution. Most often they are located on the extremities.
Anastazy Omulecki, Marek Kot, Anna Woźniacka   +2 more
doaj   +1 more source

A serum and cream moisturization regimen outperforms separate use in sustaining hydration, reducing TEWL, and balancing surface lipids over an 8‐h study

International Journal of Cosmetic Science, EarlyView.
Over 8 h, using a Hyaluronic Acid Serum in combination with a Moisturizing Cream sustained skin hydration more than either product alone, while lowering TEWL and normalizing surface lipids. Volunteers also reported a more immediate and long‐lasting moisturization with the combined regimen. Created in BioRender. Maldonado Lopez, A.
Alexandra M. Maldonado López, Ivan Domicio da Silva Souza   +1 more
wiley   +1 more source

Prevalence of hand eczema [PDF]

, 1983
This thesis describes and discusses the results of a series of investigations into the occurence of skin diseases of the hands and forearms. The problem is approached from an occupational dermatological point ofview and focuses on contacteczema ...
Coenraads, Pieter Jan, Coenraads, Pieter Jan,   +1 more
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