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Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu+7 more
wiley +1 more source
Noise‐induced synaptopathy (NIS) is largely reversible due to self‐repair. NIS and noise‐induced hidden hearing loss are two concepts with similarities and differences. The major hearing deficits in NIHHL are temporal processing disorders. The translation of animal data in NIS studies to humans is hindered by many factors.
Hui Wang, Steven J Aiken, Jian Wang
wiley +1 more source
The Morphological, Behavioral, and Transcriptomic Life Cycle of Anthrobots
DNA is thought to determine shape, behavior, and lifespan, with developmental plasticity reserved for stem cells, embryos, and species like amphibia. How much morphogenetic plasticity do adult somatic human cells exhibit? Anthrobots are a self‐organizing, motile synthetic living construct made of genetically normal human epithelial cells.
Gizem Gumuskaya+6 more
wiley +1 more source
Evaluation of Biodegradable Temporizing Matrix for Functional and Aesthetic Outcomes in Hand Soft-tissue Defect: A 3-year Retrospective Study. [PDF]
Omar UF+4 more
europepmc +1 more source
Local cold injury affecting the hand and incident Raynaud's phenomenon - a case report. [PDF]
Stjernbrandt A.
europepmc +1 more source
The Epidemiology of Metacarpal Fractures: A Descriptive Study Based on 18,802 Fractures From the Swedish Fracture Register. [PDF]
Deuschl J, Alfort H, Wilcke M.
europepmc +1 more source
Isolated Lunate Fracture in a Child: A Case Report. [PDF]
Huisman LA, Rüttermann M.
europepmc +1 more source
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Sandblasting injury of the hand
Plastic and Reconstructive Surgery, 1982Sandblasting equipment may produce serious hand injuries even though emission pressures are relatively low in comparison to forces generated by airless sprayers. This report describes a permanent injury caused by the injection of sandblast dust into the hand.
Michael F Nolan+2 more
openaire +4 more sources