Results 71 to 80 of about 3,052,093 (307)

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Hand washing knowledge and practices among public primary schools in the Kintampo Municipality of Ghana

, 2018
Background: Hand washing is very effective in preventing communicable diseases. Hand washing is particularly important for children, as they are more vulnerable to infections gained from unwashed hands and also due to their unhealthy behaviour. The study
stephen Dajaan Dubik, H. O. Addo, L. Ojo, Kingsley E. Amegah, F. Loveland, Banewel D. Bechala, Begyele B. Benjamin   +6 more
semanticscholar   +1 more source

Effect of hand washing and personal hygiene on hand food mouth disease

Medicine, 2018
There are no specific treatment drugs and vaccine for Hand Foot and Mouth Disease (HFMD). Taking effective preventive measures is particularly important for control of HFMD infection.
N. Guo, Hui-lai Ma, Jian Deng, Yanxia Ma, Liang Huang, Ruiling Guo, Lijie Zhang   +6 more
semanticscholar   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

Effect Of Nursing Compliance In Washing Hand To Phlebitis Physical Events In Graha Room Hita Husada dr Iskak Tulungagung Hospital

Journal of Nursing Practice, 2018
Bacground: Compliance of nurses in implementing a fixed procedure of nursing actions, including hand washing procedures, became one of the determinants of the success of prevention of nosocomial infections.
Aprin Rusmawati, Dedi Eko Subekti, Heri Saputro   +2 more
doaj   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

A survey of hand-washing facilities in the outpatient department of a tertiary care teaching hospital in India

Journal of Infection in Developing Countries, 2010
Introduction: Inadequate hand-washing facilities have been reported as a barrier to hand washing. This study aimed to evaluate the availability and accessibility of hand-washing facilities and supplies of hand-washing agents in the outpatient department
Mahesh Devnani, Rajiv Kumar, Rakesh Kumar Sharma, Anil Kumar Gupta   +3 more
doaj   +1 more source

Knowledge, attitude and practice on hand washing and associated factors among public primary schools children in Hosanna town, Southern Ethiopia

Journal of Public Health and Epidemiology, 2018
The burden of communicable diseases within developing countries is mainly influenced by poor personal hygiene practices Despite substantial evidence about the effectiveness of hand washing, especially using soap at all critical time, the practice is poor
Seyum Buda Alula, Ermias Mekengo Dejene, M. Terefe, A. Abinet, Mekonnen Bazie   +4 more
semanticscholar   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

FEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo, Marina Verkhovskaya, Coralie Di Scala, Claudio Rivera, Tommi Kajander   +4 more
wiley   +1 more source