Results 111 to 120 of about 61,883 (287)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Handedness in twins: Meta-Analyses
, 2020 Handedness represents an individual’s preference for the use of a hand or the relative difference in skill between the two hands. The majority of individuals prefer to use the right hand but the ontogenesis of this phenomenon is not well understood.
Lena Sophie Pfeifer
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
The economic consequences of being left-handed: some sinister results [PDF]
This paper provides the first estimates of the effects of handedness on hourly earnings. Augmenting a conventional earnings equation with an indicator of left handedness shows there is a well determined positive effect on male earnings with non-manual ...
Vincent O'Sullivan, Kevin Denny
core +2 more sources
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Fifty Years of Handedness Research: A Neurological and Methodological Update
Brain SciencesHandedness, a complex human aspect that reflects the functional lateralization of the hemispheres, also interacts with the immune system. This study aimed to expand the knowledge of the lateralization of hand, foot, and eye activities in patients with ...
Anna Rita Giovagnoli, Alessandra Parisi
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Understanding Small-Handedness
, 2017 Small-handedness continues to be overlooked, discounted, or else treated as a stigmatized disability to the present day. Chapter 1 provides the reader with a historical context for understanding the nature of small-handedness and its impact upon piano ...
Lora Deahl, Brenda Wristen
core +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Associations between handedness and brain functional connectivity patterns in children
Nature CommunicationsHandedness develops early in life, but the structural and functional brain connectivity patterns associated with it remains unknown. Here we investigate associations between handedness and the asymmetry of brain connectivity in 9- to 10-years old ...
Dardo Tomasi, Nora D. Volkow
doaj +1 more source