Results 81 to 90 of about 119,246 (323)

Pumping for gestural origins: The well may be rather dry. [PDF]

open access: yes, 2003
Corballis's explanation for right-handedness in humans relies heavily on the gestural protolanguage hypothesis, which he argues for by a series of “intuition pumps.” Scrutinizing the mirror system hypothesis and modern gesture as components of the ...
Dale, RA, Owren, MJ, Richardson, DC
core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Left- handedness versus right-handedness

open access: yes, 2020
I am left-handed. I always wonder why people who write with their right hands react so violently seeing me operating with my left hand and often ask such questions as "How do you do this?", "Do you feel comfortable?" So I want to figure out how left-handed children differ from children who write with their right hand.
Ivanova, D.   +1 more
openaire   +1 more source

Extracting the Groupwise Core Structural Connectivity Network: Bridging Statistical and Graph-Theoretical Approaches [PDF]

open access: yes, 2017
Finding the common structural brain connectivity network for a given population is an open problem, crucial for current neuro-science. Recent evidence suggests there's a tightly connected network shared between humans.
A Abraham   +10 more
core   +4 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Laterality and cognition: Handedness as a factor differentiating cognitive abilities

open access: yesDialogues in Clinical Neuroscience & Mental Health, 2018
Laterality refers to humans’ tendency to prefer one side of their body instead of the other. Τhe inborn lateralization of cerebral hemispheres is most often expressed through the humans’ handedness.
Fotini Bonoti, Filippos Vlachos
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Handedness and Intelligence

open access: yesCortex, 1978
The scores of 37 right and 30 left-handed subjects on tests of fluid and crystallized intelligence were compared. Consistent with the hypothesis, it was found that the left-handers were inferior to the right-handers on the Gf task. These data are consistent with those from three earlier studies and serve to question the assertion that there are no ...
R A, Hicks, R, Beveridge
openaire   +2 more sources

ARE LEFT HANDED SURGEONS LEFT OUT? [PDF]

open access: yes, 2012
Being a left-handed surgeon, more specifically a left-handed ENT surgeon, presents a unique pattern of difficulties.This article is an overview of left-handedness and a personal account of the specific difficulties a left-handed ENT surgeon faces. 
Kothandaraman, SriKamkshi   +1 more
core   +1 more source

Home - About - Disclaimer - Privacy