Results 81 to 90 of about 61,883 (287)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Exome-wide analysis implicates rare protein-altering variants in human handedness

open access: yesNature Communications
Handedness is a manifestation of brain hemispheric specialization. Left-handedness occurs at increased rates in neurodevelopmental disorders. Genome-wide association studies have identified common genetic effects on handedness or brain asymmetry, which ...
Dick Schijven   +3 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Handedness in autism spectrum disorders and intellectually disabled children and adolescents - Contrasting caregivers’ reports with assessments of hand preference

open access: yesHeliyon
Background: A higher rate of atypical handedness prevalence (non-right-handedness or left-, mixed-hand dominance) has been recurrently reported in individuals diagnosed with autism spectrum disorder (ASD) compared to individuals with other types of ...
Sayyed Ali Samadi
doaj   +1 more source

Laterality and cognition: Handedness as a factor differentiating cognitive abilities

open access: yesDialogues in Clinical Neuroscience & Mental Health, 2018
Laterality refers to humans’ tendency to prefer one side of their body instead of the other. Τhe inborn lateralization of cerebral hemispheres is most often expressed through the humans’ handedness.
Fotini Bonoti, Filippos Vlachos
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Broadband transparent chiral mirrors: Design methodology and bandwidth analysis

open access: yesAIP Advances, 2019
Chiral mirrors are a class of metamaterials that reflect circularly polarized light of a certain helicity in a handedness-preserving manner, while absorbing circular polarization of the opposite handedness.
Wending Mai   +6 more
doaj   +1 more source

The relationship between handedness and academic achievement in high school students of Sanandaj City, Iran

open access: yesChronic Diseases Journal, 2019
BACKGROUND: Academic achievement is considered as one of the main results of the educational system and focusing on factors affecting it is of great importance. The present study was performed with the aim to determine the relationship between handedness
Boshra Vahabi
doaj   +1 more source

Handedness and Child Development [PDF]

open access: yes
Left-handedness is historically associated with poorer outcomes for adults. Yet recent work has suggested that there may be positive labour market returns for left-handed males.
Katharina Janke   +2 more
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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