Results 51 to 60 of about 25,269 (263)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A study on the correlation between handgrip strength and blood pressure among rural children aged 7-13 in Shiyan City [PDF]

open access: yesXin yixue
Objective To investigate the current status of maximal handgrip strength in school-aged children and its correlation with blood pressure, thereby enriching the evidence on the relationship between muscular health and cardiometabolic factors in children ...
RUAN Banyin, LI Jiale, CHENG Menghan, CHEN Shengyi, PAN Yue, ZHANG Miao
doaj   +1 more source

Association between changes in handgrip strength and depression in Korean adults: a longitudinal panel study

open access: yesScientific Reports, 2022
Depression in older adults is a global socioeconomic burden. Identifying factors, such as physical activity or exercise that can help prevent depression is important.
Hyunkyu Kim   +5 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

EFFECT OF WRIST WRAP IN HANDGRIP STRENGTH IN CROSSFIT

open access: yesActa Ortopédica Brasileira, 2023
ABSTRACT Objectives: Analyze wrist wrap influence on the values of maximum handgrip strength and dynamic resistance. Methods: A controlled randomized cross-over trial including 54 Crossfit participants randomly assigned to two groups. Group 1 began the series of tests with control wrapping, and Group 2 started with functional wrapping.
Renan Lyuji Takemura   +5 more
openaire   +4 more sources

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Handgrip strength in older adults and driving aptitude

open access: yesRevista Brasileira de Enfermagem, 2023
ABSTRACT Objective: to analyze handgrip strength as a predictor of the inability to drive in older adults. Method: a cross-sectional study conducted in traffic clinics with 421 older adults in Curitiba-Paraná from January 2015 to December 2018. A sociodemographic and clinical questionnaire, handgrip strength test, and queries from the National ...
Maria Helena Lenardt   +5 more
openaire   +5 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Handgrip strength of Australian adults

open access: yes, 2023
Louise Myles studied how and why Australian adult Handgrip strength is assessed including what factors most strongly predict handgrip strength. Biological factors (age, gender, height, hand length and width and forearm circumference) and functional factors (work and lifestyle demands) have a significant influence on HGS and should be considered when ...
openaire   +2 more sources

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