Results 51 to 60 of about 25,269 (263)
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
A study on the correlation between handgrip strength and blood pressure among rural children aged 7-13 in Shiyan City [PDF]
Objective To investigate the current status of maximal handgrip strength in school-aged children and its correlation with blood pressure, thereby enriching the evidence on the relationship between muscular health and cardiometabolic factors in children ...
RUAN Banyin, LI Jiale, CHENG Menghan, CHEN Shengyi, PAN Yue, ZHANG Miao
doaj +1 more source
Depression in older adults is a global socioeconomic burden. Identifying factors, such as physical activity or exercise that can help prevent depression is important.
Hyunkyu Kim +5 more
doaj +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
EFFECT OF WRIST WRAP IN HANDGRIP STRENGTH IN CROSSFIT
ABSTRACT Objectives: Analyze wrist wrap influence on the values of maximum handgrip strength and dynamic resistance. Methods: A controlled randomized cross-over trial including 54 Crossfit participants randomly assigned to two groups. Group 1 began the series of tests with control wrapping, and Group 2 started with functional wrapping.
Renan Lyuji Takemura +5 more
openaire +4 more sources
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Handgrip strength in older adults and driving aptitude
ABSTRACT Objective: to analyze handgrip strength as a predictor of the inability to drive in older adults. Method: a cross-sectional study conducted in traffic clinics with 421 older adults in Curitiba-Paraná from January 2015 to December 2018. A sociodemographic and clinical questionnaire, handgrip strength test, and queries from the National ...
Maria Helena Lenardt +5 more
openaire +5 more sources
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Handgrip strength of Australian adults
Louise Myles studied how and why Australian adult Handgrip strength is assessed including what factors most strongly predict handgrip strength. Biological factors (age, gender, height, hand length and width and forearm circumference) and functional factors (work and lifestyle demands) have a significant influence on HGS and should be considered when ...
openaire +2 more sources

