Results 101 to 110 of about 4,098,153 (330)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The operation of agricultural tractor with universal ecological oil
Research in Agricultural Engineering, 2013 This contribution presents the results of the research into the characteristics of ecological oil labelled MOL Farm UTTO Synt in the tractor operating conditions.
J. Kosiba +4 more
doaj +1 more source
Planar microfluidics - liquid handling without walls
, 2001 The miniaturization and integration of electronic circuitry has not only made the enormous increase in performance of semiconductor devices possible but also spawned a myriad of new products and applications ranging from a cellular phone to a personal ...
Adamson +34 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Material handling systems for the fluidized-bed combustion boiler at Rivesville, West Virginia [PDF]
, 1977 The 300,000 lbs/hr steam capacity multicell fluidized-bed boiler (MFB) utilizes complex material handling systems. The material handling systems can be divided into the following areas: (1) coal preparation; transfer and delivery, (2) limestone handling ...
Branam, J. G., Rosborough, W. W.
core +1 more source
Scientific Reports, 2019 Handling can stimulate stress and anxiety in laboratory animals that negatively impacts welfare and introduces a confounding factor in many areas of research.
Kelly Gouveia, J. Hurst
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Thermodynamics of combustion gases from biogas
Research in Agricultural Engineering, 2016 Biogas as a respected source of renewable energy is used in various areas for heating or in power cogeneration units. It is produced by anaerobic fermentation of biodegradable materials.
I. Vitázek +4 more
doaj +1 more source
, 1969 Commercially available roller type desk pad provides an efficient and orderly manner of handling rolled paper tapes for proofreading. The fixture, which is modified to accept Flex-O-Writer or similar tapes and roll them in either direction, reduces the ...
core +1 more source