Results 121 to 130 of about 4,098,153 (330)

Passenger car handling model validation using LMS-DADS [PDF]

open access: yes, 2006
This paper presents the modeling and validation of a multibody passenger car model to evaluate the handling performance. LMSDADS generated the multibody passenger car model with PROTON WAJA as the benchmark.
Hudha, Khisbullah   +2 more
core  

Quality-Driven Disorder Handling for M-way Sliding Window Stream Joins

open access: yes, 2017
Sliding window join is one of the most important operators for stream applications. To produce high quality join results, a stream processing system must deal with the ubiquitous disorder within input streams which is caused by network delay ...
Fetzer, Christof   +5 more
core   +1 more source

Optimising reliability of mouse performance in behavioural testing: the major role of non-aversive handling

open access: yesScientific Reports, 2017
Handling laboratory animals during test procedures is an important source of stress that may impair reliability of test responses. Picking up mice by the tail is aversive, stimulating stress and anxiety.
Kelly Gouveia, J. Hurst
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

The CDF Data Handling System

open access: yes, 2003
The Collider Detector at Fermilab (CDF) records proton-antiproton collisions at center of mass energy of 2.0 TeV at the Tevatron collider. A new collider run, Run II, of the Tevatron started in April 2001.
Litvintsev, Dmitry
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Social facilitation revisited: increase in foraging efforts and synchronization of running in domestic chicks

open access: yesFrontiers in Neuroscience, 2011
Social influences on foraging efforts were examined in domestic chicks by investigating the frequency of runs made to feeders and the amount of pecking to gain food.
Yukiko eOgura, Toshiya eMatsushima
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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