Results 81 to 90 of about 837,729 (288)

Aeromechanical stability analysis of COPTER [PDF]

open access: yes
A plan was formed for developing a comprehensive, second-generation system with analytical capabilities for predicting performance, loads and vibration, handling qualities, aeromechanical stability, and acoustics.
Yen, Jing G., Yin, Sheng K.
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Nonlinear Control of Active Four Wheel Steer-By-Wire Vehicles

open access: yesIEEE Access, 2019
In this paper, a nonlinear triple-step steering controller for four wheel steer-by-wire vehicles has been presented to enhance handling stability. The proposed nonlinear triple-step steering controller commands the front and rear steering angles so as to
Shuyou Yu   +3 more
doaj   +1 more source

Handling qualities aspects of NASA YF-12 flight experience [PDF]

open access: yes
The handling qualities of the YF-12 airplane as observed during NASA research flights over the past five years were reviewed. Aircraft behavior during takeoff, acceleration, climb, cruise, descent, and landing are discussed. Pilot comments on the various
Berry, D. T.   +2 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Advances in Transient Stability-Constrained Optimal Power Flow of Power Systems

open access: yesCSEE Journal of Power and Energy Systems
Transient stability-constrained optimal power flow (TSCOPF) optimizes power flow while ensuring stability against potential contingencies. The main challenges faced by TSCOPF are the handling of transient constraints.
Hang Zhang, Yan Xu, Zhao Yang Dong
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Distributed-Drive Vehicle Lateral-Stability Coordinated Control Based on Phase-Plane Stability Region

open access: yesWorld Electric Vehicle Journal
The lateral stability control of vehicles is one of the most crucial aspects of vehicle safety. This article introduces a coordinated-control strategy designed to enhance the handling stability of distributed-drive electric vehicles. The upper controller
Jun Liu, Ang Dai
doaj   +1 more source

Effects of control laws and relaxed static stability on vertical ride quality of flexible aircraft [PDF]

open access: yes
State variable techniques are utilized to generate the RMS vertical load factors for the B-52H and B-1 bombers at low level, mission critical, cruise conditions.
Hinsdale, A. J.   +3 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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