Results 41 to 50 of about 153,487 (228)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Research on subjective bias cognition effect in handwriting identification
Journal of Forensic Science and Medicine, 2018 This article starts from the point of view that handwriting examination is dependent on empiricism and by analyzing the core steps of handwriting identification explains that it might be influenced by subjective bias.
Bing Li, Tiantian Ma
doaj +1 more source
, 2019 Offline Signature Verification (OSV) is a challenging pattern recognition task, especially when it is expected to generalize well on the skilled forgeries that are not available during the training.
Araabi, Babak N. +3 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Novice Ideas: Handwriting Comparisons Conducted by an Untrained Individual [PDF]
, 2019 Forensic analysis of questioned documents includes chemical analyses of paper and ink as well as handwriting comparisons. Several elements affect handwriting analyses, including the presence of discriminatory factors that can individualize a handwriting ...
Lister, Maia
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Handwriting styles: benchmarks and evaluation metrics
, 2018 Evaluating the style of handwriting generation is a challenging problem, since it is not well defined. It is a key component in order to develop in developing systems with more personalized experiences with humans.
Bailly, Gerard +2 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source