Results 81 to 90 of about 3,076,819 (327)

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Early Diagnosis of Dysgraphia in Children Based on Handwriting Image Using AI

IEEE Access
Dysgraphia is a neurological learning disability that hampers handwriting skills in children and often remains undiagnosed due to limited awareness and the absence of scalable diagnostic tools.
K. Namitha, M. Geetha, P. A. Abekaesh, Nikhil N. Kartha, G. Dhanush Kumar   +4 more
doaj   +1 more source

Handwriting Intra-Variability Across Surface Transitions: Implications for Writer Identification [PDF]

Handwriting exhibits intra-variability within the same writer due to friction between different writing surfaces, such as transitioning from paper to a computer tablet.
Chaudhuri, BB, Adak, C, Priya, K, Blumenstein, M   +3 more
core   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Unravelling handwriting images: deep neural models for dyslexia, dysgraphia, and other learning disabilities detections and classifications: a literature review [PDF]

PeerJ Computer Science
Background As a crucial cognitive and motor function, handwriting can reveal dyslexia, dysgraphia, and other neurodevelopmental conditions. With the emergence of AI, deep learning (DL) models can analyze handwriting patterns for early identification and ...
Ahmad Hamed Al Abadleh, Khalil Hamdi Ateyeh Al-Shqeerat, Mujeeb Ahmed Shaikh, Abdul Rahaman Wahab Sait   +3 more
doaj   +2 more sources

Damaging Similarities in Highly Skilled Signature Simulations - Their Detection and Authorship

Arab Journal of Forensic Sciences & Forensic Medicine, 2020
Questioned document examination is a highly specialized and challenging field of study, because of the variety and complexity of problems that are referred to document examiners. Detection and identification of practiced simulated forgeries is an area of
Mahesh C. Joshi, Mohinder Singh, Trilochan Joshi   +2 more
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

The Identification of One's Own Handwriting

Journal of Criminal Law and Criminology (1931-1951), 1943
In the field of law the principal problem concerning handwriting is the recognition or identification of samples of handwriting submitted as evidence. In decided contrast to the subjective analyses of graphologists are the objective investigations by examiners of questioned documents. Representative of the experts in the field is Albert S.
Britt, Steuart Henderson, Mensh, Ivan N.
openaire   +2 more sources

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source