Results 31 to 40 of about 42,988 (298)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Young children's perspectives of time: New directions for co‐constructing understandings of quality in ECEC

open access: yesBritish Educational Research Journal, EarlyView., 2023
Abstract Children's relationship with time in preschools is an under‐researched area. Young children rarely know how to measure time using a clock, but their experiences of time may contribute to understanding children's well‐being and debates about quality in preschools.
Kristín Dýrfjörð   +3 more
wiley   +1 more source

O ético da condição humana na era da civilização tecnológica

open access: yesINTERthesis, 2009
http://dx.doi.org/10.5007/1807-1384.2009v6n1p48   A dimensão ética da condição humana em nossa época ocupa cada vez mais os espaços das discussões filosóficas. Neste cenário, o princípio da responsabilidade vem sendo amplamente pesquisado, sobretudo, por
Angela Luzia Miranda
doaj   +1 more source

Ética e técnica: esboço de uma crítica heideggeriana à ética jonasiana

open access: yesFilosofia Unisinos, 2020
Ainda que reconhecendo o mérito da proposta de Hans Jonas em postular uma ética no contexto atual, o presente artigo elabora um esboço crítico da sua teoria da ação com base na leitura heideggeriana sobre a relação entre ética e técnica.
Angela Luzia Miranda
doaj   +1 more source

HANS JONAS ON THE ETHICS OF TECHNOLOGY

open access: yesJurnal Muara Ilmu Sosial, Humaniora, dan Seni, 2020
This paper highlights Hans Jonas' technological ethic. For Jonas, traditional ethics is no longer adequate because the dynamics of modern technology are increasingly sophisticated. Initially, technology only helped humans learn natural laws so that nature could be used by humans according to their needs.
openaire   +3 more sources

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

open access: yesFEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski   +13 more
wiley   +1 more source

Three-body effects in the Hoyle-state decay [PDF]

open access: yes, 2017
We use a sequential $R$-matrix model to describe the breakup of the Hoyle state into three $\alpha$ particles via the ground state of $^8\mathrm{Be}$. It is shown that even in a sequential picture, features resembling a direct breakup branch appear in the phase-space distribution of the $\alpha$ particles.
arxiv   +1 more source

Development of Ternary Magnesium Alloys for Laser Powder Bed Fusion: Optimizing Oxide Layer Thickness

open access: yesAdvanced Engineering Materials, EarlyView.
Additive manufacturing of magnesium alloys by laser is difficult because the melting point of the oxide layer is much higher than the evaporation temperature of the metal underneath. Making the oxide layer thinner can solve this problem. Alloying magnesium with strontium makes the oxide layer thinner, especially at 0.5 wt%.
Elmar Jonas Breitbach   +8 more
wiley   +1 more source

Understand the Human Being from the organic. The proposal of Jonas and Plessner

open access: yesPensamiento. Revista de Investigación e Información Filosófica, 2019
The question of man’s relationship with nature has been approached from multiple perspectives throughout the history of thought. This article offers the proposal of the thinkers Hans Jonas and Helmuth Plessner who place the man rooted in the natural ...
Juan Jesús Gutierro Carrasco
doaj   +1 more source

Assessing the Ecological Value: Monetizing Process Innovations in Tailored Forming

open access: yesAdvanced Engineering Materials, EarlyView.
This article introduces a method for evaluating the sustainability of innovations, even with limited data. The method is illustrated through an analysis of the “Tailored Forming” technology, which explores the impact of sustainability on economic value added.
Jonas Schneider   +4 more
wiley   +1 more source

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