Results 31 to 40 of about 4,863,726 (277)

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran   +17 more
wiley   +1 more source

Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study

open access: yesHepatology, EarlyView., 2022
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel   +93 more
wiley   +1 more source

Spatial approach of leprosy in the State of São Paulo, 2009-2012 [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2019
: Background: Leprosy is a chronic, infectious disease that affects the skin and the peripheral nervous system and can lead to permanent disability and/or deformity. Objectives: To identify the distribution and to quantify the spatial dependence of the
Flávia Regina Ferreira   +1 more
doaj   +1 more source

Comparison of Two Mice Strains, A/J and C57BL/6, in Caspase-1 Activity and IL-1β Secretion of Macrophage to Mycobacterium leprae Infection

open access: yesMediators of Inflammation, 2010
A/J mice were found to have amino acid differences in Naip5, one of the NOD-like receptors (NLRs) involved in the cytosolic recognition of pathogen-associated molecular patterns and one of the adaptor proteins for caspase-1 activation.
Tae Jin Kang   +4 more
doaj   +1 more source

Parallel evolution of reduced cancer risk and tumor suppressor duplications in Xenarthra

open access: yeseLife, 2022
The risk of developing cancer is correlated with body size and lifespan within species, but there is no correlation between cancer and either body size or lifespan between species indicating that large, long-lived species have evolved enhanced cancer ...
Juan Manuel Vazquez   +5 more
doaj   +1 more source

PSYCHOLOGICAL DISTRESS AMONG INDIVIDUALS WITH HANSEN'S DISEASE

open access: yesIndian Journal of Psychiatric Nursing, 2017
Hansen's disease is a nonfatal, chronic infectious disease caused by Mycobacterium leprae, whose clinical manifestations are largely confined to the skin, peripheral nervous system, upper respiratory tract and eyes.
ATS Giri   +3 more
doaj   +1 more source

Clinico-histological correlation in Hansen's disease: Three-year experience at a newly established tertiary care center in central India

open access: yesIndian Journal of Dermatology, 2018
Background: Hansen's disease is a chronic infectious disease caused by Mycobacterium leprae. It is characterized by a wide range of clinical and histological manifestations. Ridley–Jopling criteria are widely used for classifying leprosy.
Shruti Semwal   +4 more
doaj   +1 more source

Self‐Assembling Copolymers Encapsulating Single Endothelial Cells Induce Endogenous ECM Deposition and Vascular Regeneration

open access: yesAdvanced Materials, EarlyView.
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris   +11 more
wiley   +1 more source

Hansen's disease: a vanishing disease?

open access: yesMemorias do Instituto Oswaldo Cruz, 2012
The introduction, implementation, successes and failures of multidrug therapy (MDT) in all Hansen's disease endemic countries are discussed in this paper.
Sinésio Talhari   +5 more
doaj   +1 more source

Lab‐in‐a‐Tube System Integrating Hierarchically Wrinkled Electrodes and DNAzyme‐Functionalized Beads for Diagnosis of Clostridioides difficile Infection

open access: yesAdvanced Materials, EarlyView.
The point‐of‐care diagnosis of Clostridioides difficile infection remains challenging due to reliance on slow culture and amplification‐based methods. A lab‐in‐a‐tube electrochemical biosensor integrating DNAzymes, antifouling magnetic beads, and a hierarchically structured flow cell enables amplification‐ and culture‐free detection directly in stool ...
Survanshu Saxena   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy