Results 31 to 40 of about 4,863,726 (277)
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran +17 more
wiley +1 more source
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel +93 more
wiley +1 more source
Spatial approach of leprosy in the State of São Paulo, 2009-2012 [PDF]
: Background: Leprosy is a chronic, infectious disease that affects the skin and the peripheral nervous system and can lead to permanent disability and/or deformity. Objectives: To identify the distribution and to quantify the spatial dependence of the
Flávia Regina Ferreira +1 more
doaj +1 more source
A/J mice were found to have amino acid differences in Naip5, one of the NOD-like receptors (NLRs) involved in the cytosolic recognition of pathogen-associated molecular patterns and one of the adaptor proteins for caspase-1 activation.
Tae Jin Kang +4 more
doaj +1 more source
Parallel evolution of reduced cancer risk and tumor suppressor duplications in Xenarthra
The risk of developing cancer is correlated with body size and lifespan within species, but there is no correlation between cancer and either body size or lifespan between species indicating that large, long-lived species have evolved enhanced cancer ...
Juan Manuel Vazquez +5 more
doaj +1 more source
PSYCHOLOGICAL DISTRESS AMONG INDIVIDUALS WITH HANSEN'S DISEASE
Hansen's disease is a nonfatal, chronic infectious disease caused by Mycobacterium leprae, whose clinical manifestations are largely confined to the skin, peripheral nervous system, upper respiratory tract and eyes.
ATS Giri +3 more
doaj +1 more source
Background: Hansen's disease is a chronic infectious disease caused by Mycobacterium leprae. It is characterized by a wide range of clinical and histological manifestations. Ridley–Jopling criteria are widely used for classifying leprosy.
Shruti Semwal +4 more
doaj +1 more source
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris +11 more
wiley +1 more source
Hansen's disease: a vanishing disease?
The introduction, implementation, successes and failures of multidrug therapy (MDT) in all Hansen's disease endemic countries are discussed in this paper.
Sinésio Talhari +5 more
doaj +1 more source
The point‐of‐care diagnosis of Clostridioides difficile infection remains challenging due to reliance on slow culture and amplification‐based methods. A lab‐in‐a‐tube electrochemical biosensor integrating DNAzymes, antifouling magnetic beads, and a hierarchically structured flow cell enables amplification‐ and culture‐free detection directly in stool ...
Survanshu Saxena +10 more
wiley +1 more source

