Results 191 to 200 of about 4,844,901 (248)

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Hansen's disease patient in Ohio successfully treated with a monthly rifampin, minocycline, and moxifloxacin regimen: a case report. [PDF]

ASM Case Rep
Sankovic DE, Hubal AL, Alhajj MA, Anderson NW, Cherian S, Gundelly P, Ransom EM.   +6 more
europepmc   +1 more source

NMDA receptor subunit‐dependent analysis of radiprodil inhibition in neonatal male rat substantia nigra dopaminergic neurons

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Radiprodil is a GluN2B subunit selective NMDA receptor negative allosteric modulator which is currently under clinical investigation as a possible anti‐epileptic drug for paediatric use. Our goal was to investigate the inhibition of dopaminergic neuron NMDA responses by radiprodil.
Bangyuan Liu, Alasdair J. Gibb
wiley   +1 more source

Spatial associations of Hansen's disease and schistosomiasis in endemic regions of Minas Gerais, Brazil. [PDF]

PLoS Negl Trop Dis
Stephens JL, Fraga LAO, Ferreira JA, De Mondesert L, Kitron U, Clennon JA, Fairley JK.   +6 more
europepmc   +1 more source

A Review and Critique of Methods and Knowledge Gaps in Quantifying Spillover Effects from Protected Areas

Conservation Biology, EarlyView.
Abstract The sustainability of area‐based conservation initiatives depends on their value to society. Conservation often focuses inside protected areas, but the impacts of protected areas beyond their boundaries (spillovers) are critical for their social license.
Ilaria Gliottone, Teigan G. Collins, Ennis de Vos, Valeria Y. Mendez Angarita, Siwat Kongwarakom, Graeme S. Cumming   +5 more
wiley   +1 more source

Are natural resources a curse on the distributional consequences of financial development?

Contemporary Economic Policy, EarlyView.
Abstract This paper examines how natural resource dependence shapes the distributional effects of financial development in developing economies. Using a balanced panel of 90 countries from 1995 to 2022 and dynamic panel and nonlinear threshold methods, we show that financial development reduces wealth inequality when resource dependence is low, but ...
Dong‐Hyeon Kim, Shu‐Chin Lin, Peiyao Liu   +2 more
wiley   +1 more source

Person‐Reported and Continuous Glucose Monitoring (CGM) Recorded Hypoglycaemia in People With Insulin‐Treated Type 2 Diabetes and Mild to Moderate Chronic Kidney Disease; Post Hoc Analysis From the Hypo‐METRICS Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background and Aims People with diabetes and chronic kidney disease (CKD) may be at increased risk of iatrogenic hypoglycaemia. We compared rates of sensor‐detected (SDH) and person‐reported hypoglycaemia (PRH) in people with insulin‐treated Type 2 diabetes (T2D) with and without CKD in the Hypo‐METRICS study.
Julie M. B. Brøsen, Daniel Malmsiø, Patrick Divilly, Gilberte Martine‐Edith, Natalie Zaremba, Namam Ali, Rory J. McCrimmon, Simon Heller, Mark Evans, Bastiaan de Galan, Julia K. Mader, Eric Renard, Allan A. Vaag, Pratik Choudhary, Ulrik Pedersen‐Bjergaard, on behalf of the HypoRESOLVE Consortium, Andrew Pernet, Amy Aldridge, Marcia Henderson‐Wilson, Pernille Banck‐Petersen, Rikke Carstensen, Charlotte Hansen, Sharon Caunt, Sue Hudson, Chloe Husband, Fahad Arshad, Anne Farret, Anne‐Marie Marteil‐Oudrer, Manal Shbat, Lisa Crespy, Jenny Constanza Thibout, Anja Rasing, Jesper Walburgh Schimidt, Daniel Loewenstein, Renate Huijsmans, Pieter Drijver, Daniel Chapman, Jane Kennet, Anna Barnett, Jackie Lindsay   +39 more
wiley   +1 more source

RIMOXCLAMIN: New therapeutic regimen for Hansen's Disease cure based on effective sensitivity recovery. [PDF]

Braz J Infect Dis
Frade MAC, Albertino GS, Lima FR, de Paula NA, Cinto FAC, Perecin FC, Westin A, Junior WM, Lugão HB.   +8 more
europepmc   +1 more source