Results 101 to 110 of about 1,691,113 (258)

Coumarin Derivative N6 as a Novel anti-hantavirus Infection Agent Targeting AKT

open access: yesFrontiers in Pharmacology, 2021
Hantaviruses are globally emerging zoonotic viruses that can cause hemorrhagic fever with renal syndrome (HFRS) in Asia and Europe, which is primarily caused by Hantaan virus (HTNV) infection, results in profound morbidity and mortality.
Zhoupeng Li   +12 more
doaj   +1 more source

Conserved Endonuclease Function of Hantavirus L Polymerase. [PDF]

open access: yes, 2016
Hantaviruses are important emerging pathogens belonging to the Bunyaviridae family. Like other segmented negative strand RNA viruses, the RNA-dependent RNA polymerase (RdRp) also known as L protein of hantaviruses lacks an intrinsic "capping activity ...
Engler, O.   +4 more
core   +2 more sources

A nomogram and heat map based on LASSO‐Cox regression for predicting the risk of early‐stage severe fever with thrombocytopenia syndrome patients developing into critical illness at 7‐day and 14‐day

open access: yesJournal of Medical Virology, Volume 96, Issue 9, September 2024.
Abstract Severe fever with thrombocytopenia syndrome (SFTS) represents an emerging infectious disease characterized by a substantial mortality risk. Early identification of patients is crucial for effective risk assessment and timely interventions. In the present study, least absolute shrinkage and selection operator (LASSO)‐Cox regression analysis was
Hanwen Tong   +10 more
wiley   +1 more source

Hemorrhagic fever with renal syndrome in a child early age

open access: yesЖурнал инфектологии, 2021
In Russia, Hemorrhagic Fever with Renal Syndrome (HFRS) takes the leading place among all natural focal infections, the incidence rate in 2018 was 3,99 per 100 thousand population.
D. O. Ivanov   +10 more
doaj   +1 more source

THE DYNAMICS OF ORTHOHANTAVIRUS HANTAAN STRAINS REPLICATION ON THE MODEL OF MOUSE PERITONEAL MACROPHAGES

open access: yesActa Biomedica Scientifica, 2018
Orthohantaviruses (Orthohantavirus genus, Hantaviridae family) are the causative agents of a widespread natural focal infection in the  Russian Federation, hemorrhagic fever with renal syndrome (HFRS).
A. B. Pott   +3 more
doaj   +1 more source

Who is killing whom? Hantaviruses vs programmed cell death [PDF]

open access: yes, 2016
Hantaviruses belong to the Bunyaviridae family of negative stranded RNA viruses. They carry a tri-segmented genome and consist of four structural proteins.
Gupta, Shawon
core   +1 more source

Molecular diversity and phylogeny of Hantaan virus in Guizhou, China: evidence for Guizhou as a radiation center of the present Hantaan virus

open access: yesJournal of General Virology, 2008
To gain further insight into the molecular epidemiology of Hantaan virus (HTNV) in Guizhou, China, rodents were captured in this region in 2004 and 2005. In addition, serum samples were collected from four patients. Ten hantaviruses were isolated successfully in cell culture from four humans, two Apodemus agrarius, three Rattus norvegicus and one ...
Yang, Zou   +9 more
openaire   +2 more sources

Human behaviors driving disease emergence

open access: yesEvolutionary Anthropology: Issues, News, and Reviews, Volume 33, Issue 2, April 2024.
Abstract Interactions between humans, animals, and the environment facilitate zoonotic spillover—the transmission of pathogens from animals to humans. Narratives that cast modern humans as exogenous and disruptive forces that encroach upon “natural” disease systems limit our understanding of human drivers of disease.
Sagan Friant
wiley   +1 more source

cGAS–STING‐mediated novel nonclassic antiviral activities

open access: yesJournal of Medical Virology, Volume 96, Issue 2, February 2024.
Abstract Stimulatorof interferon genes (STING) is an intracellular sensor of cyclic dinucleotides involved in the innate immune response against pathogen‐ or self‐derived DNA. For years, interferon (IFN) induction of cyclic GMP–AMP synthase (cGAS)–STING has been considered as a canonical pattern defending the host from viral invasion.
Ying Hu   +4 more
wiley   +1 more source

Karakteristik Molekuler Segmen L Virus Seoul (SEOV) dari Rattus Norvegicus Asal Semarang, Jawa Tengah [PDF]

open access: yes, 2016
Seoul virus (SEOV) is one of four hantaviruses causing haemorrhagic fever with renal syndrome (HFRS). The virus was a negative single-strand RNA genome that consists of three segments, S, M, and L.
Handayani, F. D. (Farida)   +4 more
core   +1 more source

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