Results 11 to 20 of about 1,691,113 (258)

Structural Characterization of the Full-length Hantaan Virus Polymerase

PLOS Pathogens, 2023
Hantaviridae are a family of segmented negative-sense RNA viruses that contains important human and animal pathogens including Andes orthohantavirus and Hantaan orthohantavirus.
Keown JR, Carrique L, Nilsson-Payant B, Fodor E, Grimes JM.   +4 more
europepmc   +6 more sources

Hantaan virus glycoprotein Gc induces NEDD4-dependent PTEN ubiquitination and degradation to escape the restriction of autophagosomes and facilitate viral propagation. [PDF]

FASEB J
Hantaan virus (HTNV) infection causes severe hemorrhagic fever with renal syndrome (HFRS) in humans and the infectious process can be regulated by autophagy.
Lu S, Chen S, Zhang Y, Mou X, Li M, Zhu S, Chen X, Strandin TM, Jiang Y, Xiang Z, Liu Y, Xiong H, Guo D, Chen L, Li Y, Hou W, Luo F.   +16 more
europepmc   +3 more sources

Structural characterization of the full-length Hantaan virus polymerase. [PDF]

PLoS Pathogens
Hantaviridae are a family of segmented negative-sense RNA viruses that contain important human and animal pathogens. Hantaviridae contain a viral RNA-dependent RNA polymerase that replicates and transcribes the viral genome.
Jeremy R Keown, Loïc Carrique, Benjamin E Nilsson-Payant, Ervin Fodor, Jonathan M Grimes   +4 more
doaj   +3 more sources

Edging on Mutational Bias, Induced Natural Selection From Host and Natural Reservoirs Predominates Codon Usage Evolution in Hantaan Virus [PDF]

Frontiers in Microbiology, 2021
The molecular evolutionary dynamics that shape hantaviruses’ evolution are poorly understood even now, besides the contribution of virus-host interaction to their evolution remains an open question.
Galal Ata, Hao Wang, Haoxiang Bai, Xiaoting Yao, Shiheng Tao   +4 more
doaj   +3 more sources

Urinary genome detection and tracking of Hantaan virus from hemorrhagic fever with renal syndrome patients using multiplex PCR-based next-generation sequencing. [PDF]

PLoS Negl Trop Dis, 2021
Background Hantavirus infection occurs through the inhalation of aerosolized excreta, including urine, feces, and saliva of infected rodents. The presence of Hantaan virus (HTNV) RNA or infectious particles in urine specimens of patient with hemorrhagic ...
Cho S, Kim WK, No JS, Lee SH, Jung J, Yi Y, Park HC, Lee GY, Park K, Kim JA, Kim J, Lee J, Lee D, Song DH, Gu SH, Jeong ST, Song JW.   +16 more
europepmc   +4 more sources

High Serum Procalcitonin Concentrations in Patients With Hemorrhagic Fever With Renal Syndrome Caused by Hantaan Virus. [PDF]

Front Cell Infect Microbiol, 2018
Objective: This study analyzed the significance of procalcitonin (PCT) in patients with hemorrhagic fever with renal syndrome (HFRS) caused by Hantaan virus.
Fan X, Deng H, Sang J, Li N, Zhang X, Han Q, Liu Z.   +6 more
europepmc   +4 more sources

Introduction of Vaccinomics to Develop Personalized Vaccines in Light of Changes in the Usage of Hantaan Virus Vaccine (Hantavax) in Korea [PDF]

Journal of Preventive Medicine and Public Health, 2019
The Ministry of Food and Drug Safety of Korea made an official announcement in March 2018 that the total number of inoculations of Hantaan virus vaccine (Hantavax®) would change from 3 to 4. Some aspects of this decision remain controversial.
Jong-Myon Bae
doaj   +3 more sources

Development of an in-house dual RT-qPCR assay for detecting SFTSV and Hantaan virus simultaneously [PDF]

Biosafety and Health
Given the overlapping endemic regions and clinical similarities between severe fever with thrombocytopenia syndrome (SFTS) and hemorrhagic fever with renal syndrome (HFRS), we developed a dual real‐time fluorescence‐based reverse transcription ...
Xiaoyu Xue, Youde Liu, Chuan Song, Tingting Liu, Zishuai Liu, Wenjing Niu, Zhouling Jiang, Yanli Xu, Yuanyuan Zhang, Ling Lin, Zhihai Chen   +10 more
doaj   +3 more sources

A case report of empty Sella syndrome secondary to Hantaan virus infection and review of the literature. [PDF]

Medicine (Baltimore), 2020
Rationale: Bleeding in the anterior pituitary lobe leading to tissue necrosis occurs in the acute stage of severe clinical forms of hemorrhagic fever with renal syndrome (HFRS), while atrophy of the anterior pituitary lobe with diminution of the gland ...
Chen H, Li Y, Zhang P, Wang Y.
europepmc   +3 more sources

Acute Appendicitis Associated with Hantaan Virus Infection. [PDF]

Am J Trop Med Hyg, 2021
ABSTRACT. Hantaviruses are Bunyaviridae viruses that cause hemorrhagic fever with renal syndrome. Appendicitis caused by Hantaan virus has not been reported previously. An 81-year-old man who underwent laparoscopic appendectomy for suspected appendicitis based on abdominal pain, fever, hypotension, and computed tomography findings. Based on a suspicion
Lim SC, Lee YM, Kim CM, Yun NR, Kim DM.
europepmc   +4 more sources